Effects of ECM Components on Periodontal Ligament Stem Cell Differentiation Under Conditions of Disruption of Wnt and TGF-β Signaling Pathways

Effects of ECM Components on Periodontal Ligament Stem Cell Differentiation Under Conditions of Disruption of Wnt and TGF-β Signaling Pathways

Periodontitis is accompanied by inflammation that causes dysregulation of the Wnt/β-catenin and TGF-β signaling pathways. This leads to a violation of the homeostasis of periodontal tissues. Components of the extracellular matrix (ECM) are an important part of biomaterials used for the repair of per...

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Bibliographic Details
Main Authors: Alla V. Kuznetsova, Olga P. Popova, Tamara I. Danilova, Andrey V. Latyshev, Oleg O. Yanushevich, Alexey A. Ivanov
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Series:Journal of Functional Biomaterials
Subjects:
decellularized extracellular matrix
collagen I hydrogel
hyaluronic acid
fibronectin
laminin
periodontal ligament stem cell differentiation
Online Access:https://www.mdpi.com/2079-4983/16/3/94
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