A specific expression profile of LC3B and p62 is associated with nonresponse to neoadjuvant chemotherapy in esophageal adenocarcinomas.

A specific expression profile of LC3B and p62 is associated with nonresponse to neoadjuvant chemotherapy in esophageal adenocarcinomas.

Paclitaxel is a powerful chemotherapeutic drug, used for the treatment of many cancer types, including esophageal adenocarcinomas (EAC). Autophagy is a lysosome-dependent degradation process maintaining cellular homeostasis. Defective autophagy has been implicated in cancer biology and therapy resis...

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Bibliographic Details
Main Authors: Olivia Adams, Félice A Janser, Bastian Dislich, Sabina Berezowska, Magali Humbert, Christian A Seiler, Dino Kroell, Julia Slotta-Huspenina, Marcus Feith, Katja Ott, Mario P Tschan, Rupert Langer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:https://storage.googleapis.com/plos-corpus-prod/10.1371/journal.pone.0197610/1/pone.0197610.pdf?X-Goog-Algorithm=GOOG4-RSA-SHA256&X-Goog-Credential=wombat-sa%40plos-prod.iam.gserviceaccount.com%2F20210218%2Fauto%2Fstorage%2Fgoog4_request&X-Goog-Date=20210218T135232Z&X-Goog-Expires=3600&X-Goog-SignedHeaders=host&X-Goog-Signature=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