In vivo profiling of the PE/PPE proteins of Mycobacterium tuberculosis reveals diverse contributions to virulence
Mycobacterium tuberculosis (M.tb) uses a plethora of cell surface and secreted virulence factors to survive within the host. Among these are the PE/PPE proteins, a pair of secretory families that have expanded to 168 members in M.tb. Most of these proteins are poorly characterized due in part to the...
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| Main Authors: | Benjamin Koleske, Jessica Shen, Manish Gupta, William R. Bishai |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2025-06-01
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| Series: | Frontiers in Microbiology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fmicb.2025.1634229/full |
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