Causal integration of multi‐omics data with prior knowledge to generate mechanistic hypotheses
Abstract Multi‐omics datasets can provide molecular insights beyond the sum of individual omics. Various tools have been recently developed to integrate such datasets, but there are limited strategies to systematically extract mechanistic hypotheses from them. Here, we present COSMOS (Causal Oriente...
Saved in:
| Main Authors: | Aurelien Dugourd, Christoph Kuppe, Marco Sciacovelli, Enio Gjerga, Attila Gabor, Kristina B. Emdal, Vitor Vieira, Dorte B. Bekker‐Jensen, Jennifer Kranz, Eric.M.J. Bindels, Ana S.H. Costa, Abel Sousa, Pedro Beltrao, Miguel Rocha, Jesper V. Olsen, Christian Frezza, Rafael Kramann, Julio Saez‐Rodriguez |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Springer Nature
2021-01-01
|
| Series: | Molecular Systems Biology |
| Subjects: | |
| Online Access: | https://doi.org/10.15252/msb.20209730 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Pan‐Cancer landscape of protein activities identifies drivers of signalling dysregulation and patient survival
by: Abel Sousa, et al.
Published: (2023-01-01) -
Hypothèses
by: Christophe Blanquie
Published: (2021-03-01) -
REACT to NHST: Sensible conclusions for meaningful hypotheses
by: Izbicki, Rafael, et al.
Published: (2025-07-01) -
Hypotheses of development and strategies for overcoming drug resistance in epilepsy. Part I: Hypotheses of development
by: A. M. Yakimov, et al.
Published: (2025-01-01) -
On conditions of validity of diagnostic hypotheses
by: Ye. M. Dun
Published: (2011-06-01)