Efficacy of high doses of intravenous fosfomycin for treatment of urinary tract infection caused by KPC carbapenemase-producing Klebsiella pneumoniae: An observational study

Efficacy of high doses of intravenous fosfomycin for treatment of urinary tract infection caused by KPC carbapenemase-producing Klebsiella pneumoniae: An observational study

ABSTRACT: Objective: To evaluate the efficacy of high-dose intravenous fosfomycin for the treatment of urinary tract infections (UTI) caused by KPC carbapenemase-producing Klebsiella pneumoniae (KPC-Kp). A secondary objective was to evaluate the impact of the results of fosfomycin susceptibility te...

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Main Authors: Jorge Rodríguez-Gómez, Irene Gracia-Ahufinger I, Rosario Carmona-Flores, Julia Guzmán-Puche, Rafael León, Elena Pérez-Nadales, Monserrat Muñoz de la Rosa, Alejandra Mendez Natera, Juan José Castón, Ángela Cano, Juan Jesús Pineda-Capitán, Cristina López, Carmen De la Fuente-Martos, Julián Torre-Cisneros, Luis Martínez-Martínez
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:Journal of Global Antimicrobial Resistance
Subjects:
KPC
Carbapenemase
Fosfomycin
Urinary tract infection
Online Access:http://www.sciencedirect.com/science/article/pii/S2213716524004764
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