Specificity of treatment is mandatory in very old patients with hairy cell leukemia
Introduction. There are only a few available data about hairy cell leukemia (HCL) in very old patients. We presented three very different cases of HCL in very old patients diagnosed in a single center and discussed some epidemiological and therapeutical issues in such patients. Case report....
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| Format: | Article |
| Language: | English |
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Ministry of Defence of the Republic of Serbia, University of Defence, Belgrade
2015-01-01
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| Series: | Vojnosanitetski Pregled |
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| Online Access: | http://www.doiserbia.nb.rs/img/doi/0042-8450/2015/0042-84501505466M.pdf |
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| _version_ | 1849396902611648512 |
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| author | Marisavljević Dragomir Marković Olivera Živković Radmila |
| author_facet | Marisavljević Dragomir Marković Olivera Živković Radmila |
| author_sort | Marisavljević Dragomir |
| collection | DOAJ |
| description | Introduction. There are only a few available data about hairy cell leukemia
(HCL) in very old patients. We presented three very different cases of HCL in
very old patients diagnosed in a single center and discussed some
epidemiological and therapeutical issues in such patients. Case report. The
first patient, 89-year-old, had symptomatic cytopenia and achieved sustained
complete remission after cladribine treatment. The second patient,
89-year-old, had asymptomatic disease with stable full blood counts during a
3-year follow-up period in which watch-and-wait policy was adopted. The third
patient, 82 years old, had two malignancies (HCL and presumably metastatic
colorectal carcinoma) and his only treatment were occasional red blood cell
transfusions and symptomatic therapy. Conclusion. The presented illustrative
examples confirm individualization of treatment is mandatory in very old
patients with HCL. |
| format | Article |
| id | doaj-art-abe6d03760804e70b698e149adbf5b02 |
| institution | Kabale University |
| issn | 0042-8450 |
| language | English |
| publishDate | 2015-01-01 |
| publisher | Ministry of Defence of the Republic of Serbia, University of Defence, Belgrade |
| record_format | Article |
| series | Vojnosanitetski Pregled |
| spelling | doaj-art-abe6d03760804e70b698e149adbf5b022025-08-20T03:39:13ZengMinistry of Defence of the Republic of Serbia, University of Defence, BelgradeVojnosanitetski Pregled0042-84502015-01-0172546646810.2298/VSP1505466M0042-84501505466MSpecificity of treatment is mandatory in very old patients with hairy cell leukemiaMarisavljević Dragomir0Marković Olivera1Živković Radmila2Clinical Hospital Center “Bežanijska kosa”, Belgrade + Faculty of Medicine, BelgradeClinical Hospital Center “Bežanijska kosa”, Belgrade + Faculty of Medicine, BelgradeClinical Hospital Center “Bežanijska kosa”, BelgradeIntroduction. There are only a few available data about hairy cell leukemia (HCL) in very old patients. We presented three very different cases of HCL in very old patients diagnosed in a single center and discussed some epidemiological and therapeutical issues in such patients. Case report. The first patient, 89-year-old, had symptomatic cytopenia and achieved sustained complete remission after cladribine treatment. The second patient, 89-year-old, had asymptomatic disease with stable full blood counts during a 3-year follow-up period in which watch-and-wait policy was adopted. The third patient, 82 years old, had two malignancies (HCL and presumably metastatic colorectal carcinoma) and his only treatment were occasional red blood cell transfusions and symptomatic therapy. Conclusion. The presented illustrative examples confirm individualization of treatment is mandatory in very old patients with HCL.http://www.doiserbia.nb.rs/img/doi/0042-8450/2015/0042-84501505466M.pdfleukemia, hairy cellaged, 80 and overtherapeuticsprognosis |
| spellingShingle | Marisavljević Dragomir Marković Olivera Živković Radmila Specificity of treatment is mandatory in very old patients with hairy cell leukemia Vojnosanitetski Pregled leukemia, hairy cell aged, 80 and over therapeutics prognosis |
| title | Specificity of treatment is mandatory in very old patients with hairy cell leukemia |
| title_full | Specificity of treatment is mandatory in very old patients with hairy cell leukemia |
| title_fullStr | Specificity of treatment is mandatory in very old patients with hairy cell leukemia |
| title_full_unstemmed | Specificity of treatment is mandatory in very old patients with hairy cell leukemia |
| title_short | Specificity of treatment is mandatory in very old patients with hairy cell leukemia |
| title_sort | specificity of treatment is mandatory in very old patients with hairy cell leukemia |
| topic | leukemia, hairy cell aged, 80 and over therapeutics prognosis |
| url | http://www.doiserbia.nb.rs/img/doi/0042-8450/2015/0042-84501505466M.pdf |
| work_keys_str_mv | AT marisavljevicdragomir specificityoftreatmentismandatoryinveryoldpatientswithhairycellleukemia AT markovicolivera specificityoftreatmentismandatoryinveryoldpatientswithhairycellleukemia AT zivkovicradmila specificityoftreatmentismandatoryinveryoldpatientswithhairycellleukemia |