Investigating the Potential Use of Glycolipid Surfactants Extracted from Microbes as Anti-Aging Compounds in Cosmetic Formulations

Introduction: Skin aging is a complex process of genetic and environmental factors, such as chemical pollution and ultraviolet radiation. There is increasing evidence that microbial surfactants can exert significant antiaging effects on the skin through various mechanisms, such as stimulating fibrob...

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Bibliographic Details
Main Authors: Amir Mohammad Bagheri, Mohammad Amin Raeisi Estabragh, Mandana Ohadi
Format: Article
Language:fas
Published: Shahid Sadoughi University of Medical Sciences 2025-06-01
Series:Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd
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Online Access:http://jssu.ssu.ac.ir/article-1-6340-en.pdf
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Summary:Introduction: Skin aging is a complex process of genetic and environmental factors, such as chemical pollution and ultraviolet radiation. There is increasing evidence that microbial surfactants can exert significant antiaging effects on the skin through various mechanisms, such as stimulating fibroblast growth, possessing high antioxidant capacity, and exhibiting desirable anti-inflammatory properties. Additionally, their biodegradable nature, high surface activity, good compatibility with the body's environment and stability against changes in temperature and pH have led to an increased interest among researchers in using these compounds for bio-medical and cosmetic-sanitary applications. The aim of this study was to investigate the potential effects of glycolipid surfactants of microbial origin as anti-aging ingredients in cosmetic-hygiene products. Conclusion: This study examined the potential applications of key glycolipid surfactants (rhamnolipids and sophorolipids) derived from microbial sources to combat skin aging. Consequently, due to features such as high antioxidant capacity, anti-inflammatory properties, stimulation of collagen biosynthesis, modulation of the metabolism of fibroblasts, and more, these substances  may serve as effective compounds to combat the aging process in cosmetic-hygiene products.
ISSN:2228-5741
2228-5733