Safety, efficacy and cost-effectiveness of outpatient versus inpatient joint arthroplasty: a systematic review and meta-analysis

Abstract Background The rise in the adoption of outpatient arthroplasty has been attributed to its cost-effectiveness, although safety concerns persist. In this meta-analysis, we compare inpatient and outpatient joint arthroplasty with a primary focus on readmission and complication rates, using exc...

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Main Authors: Nikhil Ponugoti, Henry Magill
Format: Article
Language:English
Published: BMC 2025-04-01
Series:BMC Musculoskeletal Disorders
Subjects:
Online Access:https://doi.org/10.1186/s12891-025-08510-5
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author Nikhil Ponugoti
Henry Magill
author_facet Nikhil Ponugoti
Henry Magill
author_sort Nikhil Ponugoti
collection DOAJ
description Abstract Background The rise in the adoption of outpatient arthroplasty has been attributed to its cost-effectiveness, although safety concerns persist. In this meta-analysis, we compare inpatient and outpatient joint arthroplasty with a primary focus on readmission and complication rates, using exclusively high-quality prospective data. Cost-effectiveness was used as a secondary outcome measure. Methods A literature search was performed in Medline, Embase and Cochrane Library from inception to October 2023. A predefined strategy was used to conduct a systematic review and meta-analysis. Twelve studies were deemed eligible for inclusion. These were critically appraised using RoB analysis and MINORS criteria. Overall readmission rate, readmission rate for THA, readmission rate for TKA, complication rate and cost-analysis were selected as outcomes of interest. Forest plots were extracted using RevMan 5.3.5 software. Results The twelve studies included 2470 patients, of which 1052 were outpatients and 1418 inpatient subjects undergoing arthroplasty. Forest plot analysis showed no significant difference in safety outcomes (readmission and complication rates). However, there were significantly lower costs in the outpatient group compared to the inpatient group. The results of the analysis were; overall readmission rate (Odds ratio 0.66; P= 0.29; I2=18%), readmission rate in THA (odds ratio 0.62; P=0.10; I2=51%), readmission rate in TKA (odds ratio 0.67; P=0.56; I2=0%), overall complication rate (odds ratio 0.77; P=0.12; I2=38%) and cost analysis (RR -2.88; P<0.00001; I2= 93%). Conclusions This meta-analysis demonstrates that outpatient total joint arthroplasty (TJA) is a safe option, when compared to inpatient surgery. However, it is clear that further prospective studies and long-term randomized clinical data are necessary for a more comprehensive understanding.
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spelling doaj-art-abd0a39f523a447baf51848ae7a3cb7d2025-08-20T02:16:55ZengBMCBMC Musculoskeletal Disorders1471-24742025-04-0126111110.1186/s12891-025-08510-5Safety, efficacy and cost-effectiveness of outpatient versus inpatient joint arthroplasty: a systematic review and meta-analysisNikhil Ponugoti0Henry Magill1The James Cook University HospitalChelsea and Westminster HospitalAbstract Background The rise in the adoption of outpatient arthroplasty has been attributed to its cost-effectiveness, although safety concerns persist. In this meta-analysis, we compare inpatient and outpatient joint arthroplasty with a primary focus on readmission and complication rates, using exclusively high-quality prospective data. Cost-effectiveness was used as a secondary outcome measure. Methods A literature search was performed in Medline, Embase and Cochrane Library from inception to October 2023. A predefined strategy was used to conduct a systematic review and meta-analysis. Twelve studies were deemed eligible for inclusion. These were critically appraised using RoB analysis and MINORS criteria. Overall readmission rate, readmission rate for THA, readmission rate for TKA, complication rate and cost-analysis were selected as outcomes of interest. Forest plots were extracted using RevMan 5.3.5 software. Results The twelve studies included 2470 patients, of which 1052 were outpatients and 1418 inpatient subjects undergoing arthroplasty. Forest plot analysis showed no significant difference in safety outcomes (readmission and complication rates). However, there were significantly lower costs in the outpatient group compared to the inpatient group. The results of the analysis were; overall readmission rate (Odds ratio 0.66; P= 0.29; I2=18%), readmission rate in THA (odds ratio 0.62; P=0.10; I2=51%), readmission rate in TKA (odds ratio 0.67; P=0.56; I2=0%), overall complication rate (odds ratio 0.77; P=0.12; I2=38%) and cost analysis (RR -2.88; P<0.00001; I2= 93%). Conclusions This meta-analysis demonstrates that outpatient total joint arthroplasty (TJA) is a safe option, when compared to inpatient surgery. However, it is clear that further prospective studies and long-term randomized clinical data are necessary for a more comprehensive understanding.https://doi.org/10.1186/s12891-025-08510-5OutpatientInpatientArthroplasty
spellingShingle Nikhil Ponugoti
Henry Magill
Safety, efficacy and cost-effectiveness of outpatient versus inpatient joint arthroplasty: a systematic review and meta-analysis
BMC Musculoskeletal Disorders
Outpatient
Inpatient
Arthroplasty
title Safety, efficacy and cost-effectiveness of outpatient versus inpatient joint arthroplasty: a systematic review and meta-analysis
title_full Safety, efficacy and cost-effectiveness of outpatient versus inpatient joint arthroplasty: a systematic review and meta-analysis
title_fullStr Safety, efficacy and cost-effectiveness of outpatient versus inpatient joint arthroplasty: a systematic review and meta-analysis
title_full_unstemmed Safety, efficacy and cost-effectiveness of outpatient versus inpatient joint arthroplasty: a systematic review and meta-analysis
title_short Safety, efficacy and cost-effectiveness of outpatient versus inpatient joint arthroplasty: a systematic review and meta-analysis
title_sort safety efficacy and cost effectiveness of outpatient versus inpatient joint arthroplasty a systematic review and meta analysis
topic Outpatient
Inpatient
Arthroplasty
url https://doi.org/10.1186/s12891-025-08510-5
work_keys_str_mv AT nikhilponugoti safetyefficacyandcosteffectivenessofoutpatientversusinpatientjointarthroplastyasystematicreviewandmetaanalysis
AT henrymagill safetyefficacyandcosteffectivenessofoutpatientversusinpatientjointarthroplastyasystematicreviewandmetaanalysis