Could Mesquite (<i>Prosopis juliflora</i>) Help Control Gastrointestinal Parasites in Horses?
Exploring new natural-origin antiparasitic alternatives is essential in addressing the resistance issues that have emerged due to the widespread use of chemical or synthetic antiparasitic compounds. This area remains relatively underexplored despite the increasing recognition of plants like <i>...
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MDPI AG
2025-04-01
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| author | Desiderio Rodriguez Velazquez Lucrezia Forte Jorge Antonio Varela Guerrero Tonantzin Díaz Alvarado Mona M. M. Y. Elghandour Aristide Maggiolino Pasquale De Palo Abdelfattah Z. M. Salem |
| author_facet | Desiderio Rodriguez Velazquez Lucrezia Forte Jorge Antonio Varela Guerrero Tonantzin Díaz Alvarado Mona M. M. Y. Elghandour Aristide Maggiolino Pasquale De Palo Abdelfattah Z. M. Salem |
| author_sort | Desiderio Rodriguez Velazquez |
| collection | DOAJ |
| description | Exploring new natural-origin antiparasitic alternatives is essential in addressing the resistance issues that have emerged due to the widespread use of chemical or synthetic antiparasitic compounds. This area remains relatively underexplored despite the increasing recognition of plants like <i>Prosopis juliflora</i> (mesquite) for their antiparasitic properties and nutritional value as a high-protein animal feed. This review aims to investigate the antiparasitic potential of <i>P. juliflora</i> against gastrointestinal parasites in horses. The review incorporates sources from 2005 to 2024. It was found that various phytochemical compounds from <i>P. juliflora</i>, particularly alkaloids, have demonstrated significant antiparasitic activity. Alkaloids are the most studied group due to their antibacterial, antiparasitic, and cytotoxic properties. According to the literature, the phytochemicals produced by <i>P. juliflora</i> hold promise as a potential solution for combating gastrointestinal parasites in horses. However, while preliminary findings suggest promising results, in vivo studies are necessary to evaluate the precise antiparasitic efficacy of these compounds and to determine the appropriate IC50 doses of <i>P. juliflora</i> alkaloids in horses, as well as to assess potential toxicity and side effects associated with their use. |
| format | Article |
| id | doaj-art-abccbec6157d4b05917c88ccd8621fab |
| institution | DOAJ |
| issn | 2076-2615 |
| language | English |
| publishDate | 2025-04-01 |
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| spelling | doaj-art-abccbec6157d4b05917c88ccd8621fab2025-08-20T02:59:13ZengMDPI AGAnimals2076-26152025-04-01159124510.3390/ani15091245Could Mesquite (<i>Prosopis juliflora</i>) Help Control Gastrointestinal Parasites in Horses?Desiderio Rodriguez Velazquez0Lucrezia Forte1Jorge Antonio Varela Guerrero2Tonantzin Díaz Alvarado3Mona M. M. Y. Elghandour4Aristide Maggiolino5Pasquale De Palo6Abdelfattah Z. M. Salem7Facultad de Medicina Veterinaria y Zootecnia, Universidad Autónoma del Estado de México, Toluca C.P. 50000, Estado de México, MexicoDepartment of Veterinary Medicine, University of Bari, 70010 Valenzano, ItalyFacultad de Medicina Veterinaria y Zootecnia, Universidad Autónoma del Estado de México, Toluca C.P. 50000, Estado de México, MexicoFacultad de Medicina Veterinaria y Zootecnia, Universidad Autónoma del Estado de México, Toluca C.P. 50000, Estado de México, MexicoFacultad de Medicina Veterinaria y Zootecnia, Universidad Autónoma del Estado de México, Toluca C.P. 50000, Estado de México, MexicoDepartment of Veterinary Medicine, University of Bari, 70010 Valenzano, ItalyDepartment of Veterinary Medicine, University of Bari, 70010 Valenzano, ItalyFacultad de Medicina Veterinaria y Zootecnia, Universidad Autónoma del Estado de México, Toluca C.P. 50000, Estado de México, MexicoExploring new natural-origin antiparasitic alternatives is essential in addressing the resistance issues that have emerged due to the widespread use of chemical or synthetic antiparasitic compounds. This area remains relatively underexplored despite the increasing recognition of plants like <i>Prosopis juliflora</i> (mesquite) for their antiparasitic properties and nutritional value as a high-protein animal feed. This review aims to investigate the antiparasitic potential of <i>P. juliflora</i> against gastrointestinal parasites in horses. The review incorporates sources from 2005 to 2024. It was found that various phytochemical compounds from <i>P. juliflora</i>, particularly alkaloids, have demonstrated significant antiparasitic activity. Alkaloids are the most studied group due to their antibacterial, antiparasitic, and cytotoxic properties. According to the literature, the phytochemicals produced by <i>P. juliflora</i> hold promise as a potential solution for combating gastrointestinal parasites in horses. However, while preliminary findings suggest promising results, in vivo studies are necessary to evaluate the precise antiparasitic efficacy of these compounds and to determine the appropriate IC50 doses of <i>P. juliflora</i> alkaloids in horses, as well as to assess potential toxicity and side effects associated with their use.https://www.mdpi.com/2076-2615/15/9/1245equines<i>Prosopis juliflora</i>alkaloidsanti-parasiticsphytochemicals |
| spellingShingle | Desiderio Rodriguez Velazquez Lucrezia Forte Jorge Antonio Varela Guerrero Tonantzin Díaz Alvarado Mona M. M. Y. Elghandour Aristide Maggiolino Pasquale De Palo Abdelfattah Z. M. Salem Could Mesquite (<i>Prosopis juliflora</i>) Help Control Gastrointestinal Parasites in Horses? Animals equines <i>Prosopis juliflora</i> alkaloids anti-parasitics phytochemicals |
| title | Could Mesquite (<i>Prosopis juliflora</i>) Help Control Gastrointestinal Parasites in Horses? |
| title_full | Could Mesquite (<i>Prosopis juliflora</i>) Help Control Gastrointestinal Parasites in Horses? |
| title_fullStr | Could Mesquite (<i>Prosopis juliflora</i>) Help Control Gastrointestinal Parasites in Horses? |
| title_full_unstemmed | Could Mesquite (<i>Prosopis juliflora</i>) Help Control Gastrointestinal Parasites in Horses? |
| title_short | Could Mesquite (<i>Prosopis juliflora</i>) Help Control Gastrointestinal Parasites in Horses? |
| title_sort | could mesquite i prosopis juliflora i help control gastrointestinal parasites in horses |
| topic | equines <i>Prosopis juliflora</i> alkaloids anti-parasitics phytochemicals |
| url | https://www.mdpi.com/2076-2615/15/9/1245 |
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