Comorbidities in Psoriasis, Cross-Sectional Study in Western Nepal
Introduction: Psoriasis is an immune mediated chronic inflammatory disorder with a worldwide prevalence of 0.5 to 11%. Prevalence of psoriasis in Nepal is around 3%. Psoriasis has many associated systemic diseases and conditions such as diabetes, hypertension, metabolic syndrome, hypothyroidism, of...
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Society of Dermatologists, Venereologists and Leprologists of Nepal (SODVELON)
2022-03-01
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| Series: | Nepal Journal of Dermatology, Venereology & Leprology |
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| Online Access: | https://nepjol.info/index.php/NJDVL/article/view/39306 |
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| author | Binamra Basnet Ajay Kumar Shreyasha Khadka |
| author_facet | Binamra Basnet Ajay Kumar Shreyasha Khadka |
| author_sort | Binamra Basnet |
| collection | DOAJ |
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Introduction: Psoriasis is an immune mediated chronic inflammatory disorder with a worldwide prevalence of 0.5 to 11%. Prevalence of psoriasis in Nepal is around 3%. Psoriasis has many associated systemic diseases and conditions such as diabetes, hypertension, metabolic syndrome, hypothyroidism, of which the commonly associated condition is Metabolic syndrome. The objective of this study is to find the degree of association between psoriasis and other diseases such as hypothyroidism metabolic syndrome etc.
Materials and Methods: For this study, total number of fifty-two patients with equal number of age and sex matched controls were recruited with a total duration of study being six months. This is an observational cross sectional prospective study. For the qualitative data, Chi-square test was used and for quantitative data analysis Student’s t test was used.
Results: Out of the eight parameters [BMI, smoking, alcohol use, hypothyroidism, hypertension, fasting blood sugar(FBS),fasting triglyceride(TG), fasting high density lipoprotein] considering the p value of <0.05 to be significant, FBS & fasting TG were found to be significant. When the means of FBS and fasting TG were compared between the cases and controls, there was notable relationship between the difference of means and the standard errors of means (p value=0.01 for FBS and p value=0.017 for fasting TG) as calculated by Student’s t Test.
Conclusion: In this study, there was a statistical significance between the fasting blood sugar(FBS) levels of the cases and controls (p value=0.01) and also between the fasting triglyceride levels of cases and controls (p value=0.017).
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| format | Article |
| id | doaj-art-abcad33fe3b241daae052016bc22f8df |
| institution | Kabale University |
| issn | 2091-0231 2091-167X |
| language | English |
| publishDate | 2022-03-01 |
| publisher | Society of Dermatologists, Venereologists and Leprologists of Nepal (SODVELON) |
| record_format | Article |
| series | Nepal Journal of Dermatology, Venereology & Leprology |
| spelling | doaj-art-abcad33fe3b241daae052016bc22f8df2025-08-24T10:05:54ZengSociety of Dermatologists, Venereologists and Leprologists of Nepal (SODVELON)Nepal Journal of Dermatology, Venereology & Leprology2091-02312091-167X2022-03-01201Comorbidities in Psoriasis, Cross-Sectional Study in Western NepalBinamra Basnet0https://orcid.org/0000-0002-2498-6519Ajay Kumar1Shreyasha Khadka2Manipal College of Medical Sciences, Pokhara, NepalManipal College of Medical Sciences, Pokhara, NepalManipal College of Medical Sciences, Pokhara, Nepal Introduction: Psoriasis is an immune mediated chronic inflammatory disorder with a worldwide prevalence of 0.5 to 11%. Prevalence of psoriasis in Nepal is around 3%. Psoriasis has many associated systemic diseases and conditions such as diabetes, hypertension, metabolic syndrome, hypothyroidism, of which the commonly associated condition is Metabolic syndrome. The objective of this study is to find the degree of association between psoriasis and other diseases such as hypothyroidism metabolic syndrome etc. Materials and Methods: For this study, total number of fifty-two patients with equal number of age and sex matched controls were recruited with a total duration of study being six months. This is an observational cross sectional prospective study. For the qualitative data, Chi-square test was used and for quantitative data analysis Student’s t test was used. Results: Out of the eight parameters [BMI, smoking, alcohol use, hypothyroidism, hypertension, fasting blood sugar(FBS),fasting triglyceride(TG), fasting high density lipoprotein] considering the p value of <0.05 to be significant, FBS & fasting TG were found to be significant. When the means of FBS and fasting TG were compared between the cases and controls, there was notable relationship between the difference of means and the standard errors of means (p value=0.01 for FBS and p value=0.017 for fasting TG) as calculated by Student’s t Test. Conclusion: In this study, there was a statistical significance between the fasting blood sugar(FBS) levels of the cases and controls (p value=0.01) and also between the fasting triglyceride levels of cases and controls (p value=0.017). https://nepjol.info/index.php/NJDVL/article/view/39306AdipokinesComorbiditiesDiabetesDyslipidemiaHypertensionHypothyroidism |
| spellingShingle | Binamra Basnet Ajay Kumar Shreyasha Khadka Comorbidities in Psoriasis, Cross-Sectional Study in Western Nepal Nepal Journal of Dermatology, Venereology & Leprology Adipokines Comorbidities Diabetes Dyslipidemia Hypertension Hypothyroidism |
| title | Comorbidities in Psoriasis, Cross-Sectional Study in Western Nepal |
| title_full | Comorbidities in Psoriasis, Cross-Sectional Study in Western Nepal |
| title_fullStr | Comorbidities in Psoriasis, Cross-Sectional Study in Western Nepal |
| title_full_unstemmed | Comorbidities in Psoriasis, Cross-Sectional Study in Western Nepal |
| title_short | Comorbidities in Psoriasis, Cross-Sectional Study in Western Nepal |
| title_sort | comorbidities in psoriasis cross sectional study in western nepal |
| topic | Adipokines Comorbidities Diabetes Dyslipidemia Hypertension Hypothyroidism |
| url | https://nepjol.info/index.php/NJDVL/article/view/39306 |
| work_keys_str_mv | AT binamrabasnet comorbiditiesinpsoriasiscrosssectionalstudyinwesternnepal AT ajaykumar comorbiditiesinpsoriasiscrosssectionalstudyinwesternnepal AT shreyashakhadka comorbiditiesinpsoriasiscrosssectionalstudyinwesternnepal |