Human dorsal forebrain organoids show differentiation-state-specific protein secretion

Human dorsal forebrain organoids show differentiation-state-specific protein secretion

Summary: The human brain microenvironment undergoes dynamic changes during development, which have been incompletely characterized in in vitro models including neural organoids. Here, we used liquid chromatography-mass spectrometry to investigate proteome and secretome changes in human dorsal forebr...

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Bibliographic Details
Main Authors: Zeynep Yentür, Theresa Kagermeier, Kseniia Sarieva, Mohamed A. Jarboui, Katharina Becker, Simone Mayer
Format: Article
Language:English
Published: Elsevier 2025-07-01
Series:iScience
Subjects:
Natural sciences
Biological sciences
Neuroscience
Tissue engineering
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004225011964
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