Intracellular trafficking of furin enhances cellular intoxication by recombinant immunotoxins based on Pseudomonas exotoxin A

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Main Authors: Brian D. Grossman, Jack D. Sanford, Yuyi Zhu, Cynthia B. Zeller, John E. Weldon
Format: Article
Language:English
Published: The Company of Biologists 2025-06-01
Series:Biology Open
Subjects:
Online Access:http://bio.biologists.org/content/14/6/bio061792
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author Brian D. Grossman
Jack D. Sanford
Yuyi Zhu
Cynthia B. Zeller
John E. Weldon
author_facet Brian D. Grossman
Jack D. Sanford
Yuyi Zhu
Cynthia B. Zeller
John E. Weldon
author_sort Brian D. Grossman
collection DOAJ
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issn 2046-6390
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publishDate 2025-06-01
publisher The Company of Biologists
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spelling doaj-art-abb738f4723d478fa160987eebf631232025-08-20T02:43:49ZengThe Company of BiologistsBiology Open2046-63902025-06-0114610.1242/bio.061792061792Intracellular trafficking of furin enhances cellular intoxication by recombinant immunotoxins based on Pseudomonas exotoxin ABrian D. Grossman0Jack D. Sanford1Yuyi Zhu2Cynthia B. Zeller3John E. Weldon4 Department of Biological Sciences, The Jess and Mildred Fisher College of Science and Mathematics, Towson University, 8000 York Rd, Towson, MD 21252, USA Department of Biological Sciences, The Jess and Mildred Fisher College of Science and Mathematics, Towson University, 8000 York Rd, Towson, MD 21252, USA Department of Biological Sciences, The Jess and Mildred Fisher College of Science and Mathematics, Towson University, 8000 York Rd, Towson, MD 21252, USA Department of Chemistry, The Jess and Mildred Fisher College of Science and Mathematics, Towson University, 8000 York Rd, Towson, MD 21252, USA Department of Biological Sciences, The Jess and Mildred Fisher College of Science and Mathematics, Towson University, 8000 York Rd, Towson, MD 21252, USA http://bio.biologists.org/content/14/6/bio061792furinpseudomonas exotoxin arecombinant immunotoxinintracellular traffickinggene knockoutcancer therapy
spellingShingle Brian D. Grossman
Jack D. Sanford
Yuyi Zhu
Cynthia B. Zeller
John E. Weldon
Intracellular trafficking of furin enhances cellular intoxication by recombinant immunotoxins based on Pseudomonas exotoxin A
Biology Open
furin
pseudomonas exotoxin a
recombinant immunotoxin
intracellular trafficking
gene knockout
cancer therapy
title Intracellular trafficking of furin enhances cellular intoxication by recombinant immunotoxins based on Pseudomonas exotoxin A
title_full Intracellular trafficking of furin enhances cellular intoxication by recombinant immunotoxins based on Pseudomonas exotoxin A
title_fullStr Intracellular trafficking of furin enhances cellular intoxication by recombinant immunotoxins based on Pseudomonas exotoxin A
title_full_unstemmed Intracellular trafficking of furin enhances cellular intoxication by recombinant immunotoxins based on Pseudomonas exotoxin A
title_short Intracellular trafficking of furin enhances cellular intoxication by recombinant immunotoxins based on Pseudomonas exotoxin A
title_sort intracellular trafficking of furin enhances cellular intoxication by recombinant immunotoxins based on pseudomonas exotoxin a
topic furin
pseudomonas exotoxin a
recombinant immunotoxin
intracellular trafficking
gene knockout
cancer therapy
url http://bio.biologists.org/content/14/6/bio061792
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