Assessment of X Chromosome Centromere Instability in Alzheimer’s Disease: A Quantitative FISH Approach

Assessment of X Chromosome Centromere Instability in Alzheimer’s Disease: A Quantitative FISH Approach

Chromosomal instability in Alzheimer’s disease (AD) neurons has been previously reported. This pilot study aimed to establish a quantitative technique for assessing X chromosome centromere signals using fluorescence in situ hybridization (FISH). Hippocampal brain tissue was collected at autopsy from...

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Bibliographic Details
Main Authors:	Biljana Spremo-Potparević, Petar Popović, Dijana Topalović, Andrea Pirković, George Perry, Lada Živković
Format:	Article
Language:	English
Published:	MDPI AG 2025-06-01
Series:	Current Issues in Molecular Biology
Subjects:	Alzheimer’s disease premature centromere division X chromosome chromosomal instability fluorescence in situ hybridization
Online Access:	https://www.mdpi.com/1467-3045/47/6/420
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