Association between the skeletal muscle-to-visceral fat ratio and kidney stones: a cross-sectional study
ObjectivePrior research has suggested links between skeletal muscle mass and visceral fat volume with kidney stone formation. However, the link between the skeletal muscle-to-visceral fat ratio (SVR) and kidney stone risk remains to be clarified. This study aims to explore the relationship between S...
Saved in:
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2025-05-01
|
| Series: | Frontiers in Nutrition |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fnut.2025.1549047/full |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849728569262997504 |
|---|---|
| author | Yuan-Zhuo Du Jia-Qing Yang Jian Tang Chi-Teng Zhang Yi-Fu Liu |
| author_facet | Yuan-Zhuo Du Jia-Qing Yang Jian Tang Chi-Teng Zhang Yi-Fu Liu |
| author_sort | Yuan-Zhuo Du |
| collection | DOAJ |
| description | ObjectivePrior research has suggested links between skeletal muscle mass and visceral fat volume with kidney stone formation. However, the link between the skeletal muscle-to-visceral fat ratio (SVR) and kidney stone risk remains to be clarified. This study aims to explore the relationship between SVR and the risk of kidney stones, analyzing data from the National Health and Nutrition Examination Survey (NHANES).MethodsThe research encompassed 8,522 individuals from NHANES surveys from 2011 to 2018. Kidney stones were diagnosed through a standardized questionnaire, and SVR was calculated using dual-energy X-ray absorptiometry (DXA). Participants were grouped into quartiles based on their SVR. All data underwent weighting according to official guidelines. Logistic regression models assessed the correlation between SVR and kidney stone incidence, and subgroup analysis was employed to investigate its stability.ResultsAmong the participants, 675 individuals, representing 8.73%, received a diagnosis of kidney stones, with an average age of 39.29 years (±0.28). Findings indicate that lower SVR correlates with increased kidney stone risk. Within the comprehensively adjusted multivariate model, compared to the lowest SVR quartile, the second, third, and fourth quartiles demonstrated significantly reduced risks, with ORs of 0.63 (95% CI = 0.47–0.84), 0.57 (95% CI = 0.42–0.79), and 0.39 (95% CI = 0.25–0.61), respectively. Restricted cubic spline (RCS) regression models demonstrated a non-linear relationship between SVR and kidney stone risk. The subgroup analysis demonstrated no significant differences in weighted associations across subgroups (interaction p-value > 0.05), except for BMI, which had a significant interaction (interaction p-value < 0.05).ConclusionThe findings underscore that lower SVR correlates with increased kidney stone risk, a relationship that remains consistent across most demographics. |
| format | Article |
| id | doaj-art-abace3d2a4ed41dab39e9a73d5556195 |
| institution | DOAJ |
| issn | 2296-861X |
| language | English |
| publishDate | 2025-05-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Nutrition |
| spelling | doaj-art-abace3d2a4ed41dab39e9a73d55561952025-08-20T03:09:31ZengFrontiers Media S.A.Frontiers in Nutrition2296-861X2025-05-011210.3389/fnut.2025.15490471549047Association between the skeletal muscle-to-visceral fat ratio and kidney stones: a cross-sectional studyYuan-Zhuo Du0Jia-Qing Yang1Jian Tang2Chi-Teng Zhang3Yi-Fu Liu4Department of Urology, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, ChinaDepartment of Urology, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, ChinaThe Second Affiliated Hospital, Department of Urology, Hengyang Medical School, University of South China, Hengyang, Hunan, ChinaThe Second Affiliated Hospital, Department of Urology, Hengyang Medical School, University of South China, Hengyang, Hunan, ChinaThe Second Affiliated Hospital, Department of Urology, Hengyang Medical School, University of South China, Hengyang, Hunan, ChinaObjectivePrior research has suggested links between skeletal muscle mass and visceral fat volume with kidney stone formation. However, the link between the skeletal muscle-to-visceral fat ratio (SVR) and kidney stone risk remains to be clarified. This study aims to explore the relationship between SVR and the risk of kidney stones, analyzing data from the National Health and Nutrition Examination Survey (NHANES).MethodsThe research encompassed 8,522 individuals from NHANES surveys from 2011 to 2018. Kidney stones were diagnosed through a standardized questionnaire, and SVR was calculated using dual-energy X-ray absorptiometry (DXA). Participants were grouped into quartiles based on their SVR. All data underwent weighting according to official guidelines. Logistic regression models assessed the correlation between SVR and kidney stone incidence, and subgroup analysis was employed to investigate its stability.ResultsAmong the participants, 675 individuals, representing 8.73%, received a diagnosis of kidney stones, with an average age of 39.29 years (±0.28). Findings indicate that lower SVR correlates with increased kidney stone risk. Within the comprehensively adjusted multivariate model, compared to the lowest SVR quartile, the second, third, and fourth quartiles demonstrated significantly reduced risks, with ORs of 0.63 (95% CI = 0.47–0.84), 0.57 (95% CI = 0.42–0.79), and 0.39 (95% CI = 0.25–0.61), respectively. Restricted cubic spline (RCS) regression models demonstrated a non-linear relationship between SVR and kidney stone risk. The subgroup analysis demonstrated no significant differences in weighted associations across subgroups (interaction p-value > 0.05), except for BMI, which had a significant interaction (interaction p-value < 0.05).ConclusionThe findings underscore that lower SVR correlates with increased kidney stone risk, a relationship that remains consistent across most demographics.https://www.frontiersin.org/articles/10.3389/fnut.2025.1549047/fullskeletal muscle-to-visceral fat ratiokidney stonesNHANEScross-sectional studyskeletal musclevisceral fat |
| spellingShingle | Yuan-Zhuo Du Jia-Qing Yang Jian Tang Chi-Teng Zhang Yi-Fu Liu Association between the skeletal muscle-to-visceral fat ratio and kidney stones: a cross-sectional study Frontiers in Nutrition skeletal muscle-to-visceral fat ratio kidney stones NHANES cross-sectional study skeletal muscle visceral fat |
| title | Association between the skeletal muscle-to-visceral fat ratio and kidney stones: a cross-sectional study |
| title_full | Association between the skeletal muscle-to-visceral fat ratio and kidney stones: a cross-sectional study |
| title_fullStr | Association between the skeletal muscle-to-visceral fat ratio and kidney stones: a cross-sectional study |
| title_full_unstemmed | Association between the skeletal muscle-to-visceral fat ratio and kidney stones: a cross-sectional study |
| title_short | Association between the skeletal muscle-to-visceral fat ratio and kidney stones: a cross-sectional study |
| title_sort | association between the skeletal muscle to visceral fat ratio and kidney stones a cross sectional study |
| topic | skeletal muscle-to-visceral fat ratio kidney stones NHANES cross-sectional study skeletal muscle visceral fat |
| url | https://www.frontiersin.org/articles/10.3389/fnut.2025.1549047/full |
| work_keys_str_mv | AT yuanzhuodu associationbetweentheskeletalmuscletovisceralfatratioandkidneystonesacrosssectionalstudy AT jiaqingyang associationbetweentheskeletalmuscletovisceralfatratioandkidneystonesacrosssectionalstudy AT jiantang associationbetweentheskeletalmuscletovisceralfatratioandkidneystonesacrosssectionalstudy AT chitengzhang associationbetweentheskeletalmuscletovisceralfatratioandkidneystonesacrosssectionalstudy AT yifuliu associationbetweentheskeletalmuscletovisceralfatratioandkidneystonesacrosssectionalstudy |