On the issue of timely diagnostics of gender formation disorders

Importance of early diagnostics of gender differentiation disorders in children is discussed, different manifestations of this pathology are described so that they could be included in the spectrum of diagnostic search. We presented a clinical observation of two patients with gender formation disord...

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Main Authors: I. L. Nikitina, E. K. Kudryashova, A. M. Todieva, R. T. Badrutdinov, A. A. Kostareva
Format: Article
Language:Russian
Published: Open Systems Publication 2021-06-01
Series:Лечащий Врач
Subjects:
Online Access:https://journal.lvrach.ru/jour/article/view/92
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author I. L. Nikitina
E. K. Kudryashova
A. M. Todieva
R. T. Badrutdinov
A. A. Kostareva
author_facet I. L. Nikitina
E. K. Kudryashova
A. M. Todieva
R. T. Badrutdinov
A. A. Kostareva
author_sort I. L. Nikitina
collection DOAJ
description Importance of early diagnostics of gender differentiation disorders in children is discussed, different manifestations of this pathology are described so that they could be included in the spectrum of diagnostic search. We presented a clinical observation of two patients with gender formation disorders with karyotype 46ХУ, with identified mutations in the same gene of steroidogenic factor NR5A1, whom, on their birth, official female gender was given.
format Article
id doaj-art-aba1f1ab0a924ccf820f788765a29b3d
institution Kabale University
issn 1560-5175
2687-1181
language Russian
publishDate 2021-06-01
publisher Open Systems Publication
record_format Article
series Лечащий Врач
spelling doaj-art-aba1f1ab0a924ccf820f788765a29b3d2025-08-20T03:57:51ZrusOpen Systems PublicationЛечащий Врач1560-51752687-11812021-06-0103172110.26295/OS.2020.83.45.00291On the issue of timely diagnostics of gender formation disordersI. L. Nikitina0E. K. Kudryashova1A. M. Todieva2R. T. Badrutdinov3A. A. Kostareva4ФГБУ НМИЦ им. В. А. Алмазова МЗ РФФГБУ НМИЦ им. В. А. Алмазова МЗ РФФГБУ НМИЦ им. В. А. Алмазова МЗ РФФГБУ НМИЦ им. В. А. Алмазова МЗ РФФГБУ НМИЦ им. В. А. Алмазова МЗ РФImportance of early diagnostics of gender differentiation disorders in children is discussed, different manifestations of this pathology are described so that they could be included in the spectrum of diagnostic search. We presented a clinical observation of two patients with gender formation disorders with karyotype 46ХУ, with identified mutations in the same gene of steroidogenic factor NR5A1, whom, on their birth, official female gender was given.https://journal.lvrach.ru/jour/article/view/92gender differentiationgenital developmentkaryotypefertility potential
spellingShingle I. L. Nikitina
E. K. Kudryashova
A. M. Todieva
R. T. Badrutdinov
A. A. Kostareva
On the issue of timely diagnostics of gender formation disorders
Лечащий Врач
gender differentiation
genital development
karyotype
fertility potential
title On the issue of timely diagnostics of gender formation disorders
title_full On the issue of timely diagnostics of gender formation disorders
title_fullStr On the issue of timely diagnostics of gender formation disorders
title_full_unstemmed On the issue of timely diagnostics of gender formation disorders
title_short On the issue of timely diagnostics of gender formation disorders
title_sort on the issue of timely diagnostics of gender formation disorders
topic gender differentiation
genital development
karyotype
fertility potential
url https://journal.lvrach.ru/jour/article/view/92
work_keys_str_mv AT ilnikitina ontheissueoftimelydiagnosticsofgenderformationdisorders
AT ekkudryashova ontheissueoftimelydiagnosticsofgenderformationdisorders
AT amtodieva ontheissueoftimelydiagnosticsofgenderformationdisorders
AT rtbadrutdinov ontheissueoftimelydiagnosticsofgenderformationdisorders
AT aakostareva ontheissueoftimelydiagnosticsofgenderformationdisorders