Potential of Soursop Leaf Extract Scrub as Antimicrobial

Treatment of infectious diseases caused by bacteria has been carried out using antibiotics. However, the problem is resistance and even multi-resistance in bacteria. Preventive efforts are needed to anticipate, one of which is using soursop leaf extract scrub herbal products which contain gamma oryz...

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Main Authors: Nyoman Jirna, Gede Sudarmanto, Nyoman Purna, Nyoman Mastra, Nyoman Gede Suyasa, Cok Dewi Widhya Hana Sundari, Ida Ayu Made Sri Arjani, Gusti Agung Ayu Satwikha Desi
Format: Article
Language:English
Published: Poltekkes Kemenkes Jakarta III 2023-09-01
Series:Jurnal Ilmu dan Teknologi Kesehatan
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Online Access:https://ejurnal.poltekkesjakarta3.ac.id/index.php/jitek/article/view/1058
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author Nyoman Jirna
Gede Sudarmanto
Nyoman Purna
Nyoman Mastra
Nyoman Gede Suyasa
Cok Dewi Widhya Hana Sundari
Ida Ayu Made Sri Arjani
Gusti Agung Ayu Satwikha Desi
author_facet Nyoman Jirna
Gede Sudarmanto
Nyoman Purna
Nyoman Mastra
Nyoman Gede Suyasa
Cok Dewi Widhya Hana Sundari
Ida Ayu Made Sri Arjani
Gusti Agung Ayu Satwikha Desi
author_sort Nyoman Jirna
collection DOAJ
description Treatment of infectious diseases caused by bacteria has been carried out using antibiotics. However, the problem is resistance and even multi-resistance in bacteria. Preventive efforts are needed to anticipate, one of which is using soursop leaf extract scrub herbal products which contain gamma oryzanol compounds, flavonoids, phenols, and tannins as antimicrobials. This research is a pure experiment with one group pretest-posttest control design and positive and negative controls. The study aims to analyse the effectiveness of soursop leaf extract scrub products as antimicrobials on the skin of the respondents' arms before and after treatment. Antimicrobial counting uses the total plate count (TPC) method, with 118 respondents in-vivo, where the scrub is applied to the respondent's arm, measuring 10cm x 10cm for 10 minutes. The results of the data normality test with the Kolmogorov-Smirnov test obtained non-normally distributed data. The trial continued with a non-parametric test in the Wilcoxon test to get a significance value of 0.000 <0.05, which means that the soursop leaf extract scrub effectively reduces total bacteria count. The research may be helpful for the community in efforts to prevent skin infections caused by bacteria, and researchers need to conduct antibacterial tests for scrubs without soursop leaf extract as a comparison and conduct further tests such as safety tests, expiration periods and aesthetic tests on soursop leaf extract scrub products.
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publisher Poltekkes Kemenkes Jakarta III
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spelling doaj-art-ab9bfab7c921457e82a73f8bb94d774c2025-08-20T02:49:09ZengPoltekkes Kemenkes Jakarta IIIJurnal Ilmu dan Teknologi Kesehatan2338-90952338-91092023-09-01111566410.32668/jitek.v11i1.10581058Potential of Soursop Leaf Extract Scrub as AntimicrobialNyoman Jirna0Gede Sudarmanto1Nyoman Purna2Nyoman Mastra3Nyoman Gede Suyasa4Cok Dewi Widhya Hana Sundari5Ida Ayu Made Sri Arjani6Gusti Agung Ayu Satwikha Desi7Jurusan Teknologi Laboratorium Medis, Poltekkes Kemenkes Mataram, IndonesiaJurusan Teknologi Laboratorium Medis, Poltekkes Kemenkes Mataram, IndonesiaJurusan Teknologi Laboratorium Medis, Poltekkes Kemenkes Mataram, IndonesiaJurusan Teknologi Laboratorium Medis, Poltekkes Kemenkes Mataram, IndonesiaJurusan Teknologi Laboratorium Medis, Poltekkes Kemenkes Mataram, IndonesiaJurusan Teknologi Laboratorium Medis, Poltekkes Kemenkes Mataram, IndonesiaJurusan Teknologi Laboratorium Medis, Poltekkes Kemenkes Mataram, IndonesiaFakultas Ilmu-Ilmu Kesehatan, Universitas Bali International, IndonesiaTreatment of infectious diseases caused by bacteria has been carried out using antibiotics. However, the problem is resistance and even multi-resistance in bacteria. Preventive efforts are needed to anticipate, one of which is using soursop leaf extract scrub herbal products which contain gamma oryzanol compounds, flavonoids, phenols, and tannins as antimicrobials. This research is a pure experiment with one group pretest-posttest control design and positive and negative controls. The study aims to analyse the effectiveness of soursop leaf extract scrub products as antimicrobials on the skin of the respondents' arms before and after treatment. Antimicrobial counting uses the total plate count (TPC) method, with 118 respondents in-vivo, where the scrub is applied to the respondent's arm, measuring 10cm x 10cm for 10 minutes. The results of the data normality test with the Kolmogorov-Smirnov test obtained non-normally distributed data. The trial continued with a non-parametric test in the Wilcoxon test to get a significance value of 0.000 <0.05, which means that the soursop leaf extract scrub effectively reduces total bacteria count. The research may be helpful for the community in efforts to prevent skin infections caused by bacteria, and researchers need to conduct antibacterial tests for scrubs without soursop leaf extract as a comparison and conduct further tests such as safety tests, expiration periods and aesthetic tests on soursop leaf extract scrub products.https://ejurnal.poltekkesjakarta3.ac.id/index.php/jitek/article/view/1058antimicrobialscrubsoursop leaf extract
spellingShingle Nyoman Jirna
Gede Sudarmanto
Nyoman Purna
Nyoman Mastra
Nyoman Gede Suyasa
Cok Dewi Widhya Hana Sundari
Ida Ayu Made Sri Arjani
Gusti Agung Ayu Satwikha Desi
Potential of Soursop Leaf Extract Scrub as Antimicrobial
Jurnal Ilmu dan Teknologi Kesehatan
antimicrobial
scrub
soursop leaf extract
title Potential of Soursop Leaf Extract Scrub as Antimicrobial
title_full Potential of Soursop Leaf Extract Scrub as Antimicrobial
title_fullStr Potential of Soursop Leaf Extract Scrub as Antimicrobial
title_full_unstemmed Potential of Soursop Leaf Extract Scrub as Antimicrobial
title_short Potential of Soursop Leaf Extract Scrub as Antimicrobial
title_sort potential of soursop leaf extract scrub as antimicrobial
topic antimicrobial
scrub
soursop leaf extract
url https://ejurnal.poltekkesjakarta3.ac.id/index.php/jitek/article/view/1058
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AT cokdewiwidhyahanasundari potentialofsoursopleafextractscrubasantimicrobial
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