Gene Therapy for Glioblastoma Multiforme

Gene Therapy for Glioblastoma Multiforme

Glioblastoma multiforme (GBM) is a devastating, aggressive primary brain tumor with poor patient outcomes and a five-year survival of less than 10%. Significant limitations to effective GBM treatment include poor drug delivery across the blood–brain barrier, drug resistance, and complex genetic tumo...

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Bibliographic Details
Main Authors: Smit Shah, Joshua Green, Shantelle A. Graff, Qi Li, John D. Heiss
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Viruses
Subjects:
glioblastoma
gene
therapy
vector
survival
Online Access:https://www.mdpi.com/1999-4915/17/1/118
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