The Zebrafish model in dermatology: an update for clinicians
Abstract Recently, the zebrafish has been established as one of the most important model organisms for medical research. Several studies have proved that there is a high level of similarity between human and zebrafish genomes, which encourages the use of zebrafish as a model for understanding human...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Springer
2022-06-01
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| Series: | Discover Oncology |
| Online Access: | https://doi.org/10.1007/s12672-022-00511-3 |
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| _version_ | 1832594641666441216 |
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| author | Irene Russo Emma Sartor Laura Fagotto Anna Colombo Natascia Tiso Mauro Alaibac |
| author_facet | Irene Russo Emma Sartor Laura Fagotto Anna Colombo Natascia Tiso Mauro Alaibac |
| author_sort | Irene Russo |
| collection | DOAJ |
| description | Abstract Recently, the zebrafish has been established as one of the most important model organisms for medical research. Several studies have proved that there is a high level of similarity between human and zebrafish genomes, which encourages the use of zebrafish as a model for understanding human genetic disorders, including cancer. Interestingly, zebrafish skin shows several similarities to human skin, suggesting that this model organism is particularly suitable for the study of neoplastic and inflammatory skin disorders. This paper appraises the specific characteristics of zebrafish skin and describes the major applications of the zebrafish model in dermatological research. |
| format | Article |
| id | doaj-art-ab98fe50bee346a6a4ada665baa52f10 |
| institution | Kabale University |
| issn | 2730-6011 |
| language | English |
| publishDate | 2022-06-01 |
| publisher | Springer |
| record_format | Article |
| series | Discover Oncology |
| spelling | doaj-art-ab98fe50bee346a6a4ada665baa52f102025-01-19T12:29:07ZengSpringerDiscover Oncology2730-60112022-06-0113111610.1007/s12672-022-00511-3The Zebrafish model in dermatology: an update for cliniciansIrene Russo0Emma Sartor1Laura Fagotto2Anna Colombo3Natascia Tiso4Mauro Alaibac5Unit of Dermatology, University of PaduaUnit of Dermatology, University of PaduaUnit of Dermatology, University of PaduaUnit of Dermatology, University of PaduaDepartment of Biology, University of PaduaUnit of Dermatology, University of PaduaAbstract Recently, the zebrafish has been established as one of the most important model organisms for medical research. Several studies have proved that there is a high level of similarity between human and zebrafish genomes, which encourages the use of zebrafish as a model for understanding human genetic disorders, including cancer. Interestingly, zebrafish skin shows several similarities to human skin, suggesting that this model organism is particularly suitable for the study of neoplastic and inflammatory skin disorders. This paper appraises the specific characteristics of zebrafish skin and describes the major applications of the zebrafish model in dermatological research.https://doi.org/10.1007/s12672-022-00511-3 |
| spellingShingle | Irene Russo Emma Sartor Laura Fagotto Anna Colombo Natascia Tiso Mauro Alaibac The Zebrafish model in dermatology: an update for clinicians Discover Oncology |
| title | The Zebrafish model in dermatology: an update for clinicians |
| title_full | The Zebrafish model in dermatology: an update for clinicians |
| title_fullStr | The Zebrafish model in dermatology: an update for clinicians |
| title_full_unstemmed | The Zebrafish model in dermatology: an update for clinicians |
| title_short | The Zebrafish model in dermatology: an update for clinicians |
| title_sort | zebrafish model in dermatology an update for clinicians |
| url | https://doi.org/10.1007/s12672-022-00511-3 |
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