ABO blood group system and occurrence of ischemic stroke

ABSTRACT Background: Ischemic stroke (IS) is a multifactorial disease that presents high rates of morbimortality in Brazil. Several studies proved that there is a link between the ABO blood group system and the occurrence of thrombotic events. Nonetheless, its association with IS is not well establi...

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Main Authors: Rafaella Chiodini LOTZ, Carolina da Silveira WELTER, Silvia Aparecida RAMOS, Leslie Ecker FERREIRA, Norberto Luiz CABRAL, Paulo Henrique Condeixa de FRANÇA
Format: Article
Language:English
Published: Thieme Revinter Publicações
Series:Arquivos de Neuro-Psiquiatria
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Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2021005024101&tlng=en
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author Rafaella Chiodini LOTZ
Carolina da Silveira WELTER
Silvia Aparecida RAMOS
Leslie Ecker FERREIRA
Norberto Luiz CABRAL
Paulo Henrique Condeixa de FRANÇA
author_facet Rafaella Chiodini LOTZ
Carolina da Silveira WELTER
Silvia Aparecida RAMOS
Leslie Ecker FERREIRA
Norberto Luiz CABRAL
Paulo Henrique Condeixa de FRANÇA
author_sort Rafaella Chiodini LOTZ
collection DOAJ
description ABSTRACT Background: Ischemic stroke (IS) is a multifactorial disease that presents high rates of morbimortality in Brazil. Several studies proved that there is a link between the ABO blood group system and the occurrence of thrombotic events. Nonetheless, its association with IS is not well established. Objective: For that reason, the purpose hereof was to investigate the relation between the ABO blood groups and the occurrence of IS in a Brazilian cohort of cerebrovascular diseases. Methods: Five hundred and twenty-nine subjects were included over 12 months, from which 275 presented an IS episode and 254 composed the control group. Blood samples were drawn for direct and reverse serotyping. The control and IS groups were compared regarding the traditional risk factors and the distribution of the ABO blood groups. Results: The IS group presented a higher prevalence of systemic arterial hypertension (SAH), diabetes mellitus, smoking habits, family history, cardiopathy, and sedentary lifestyle in comparison with the control group. The AB blood type prevailed among the patients (5.1 vs. 1.6%; p<0.05) and this group had more SAH cases in comparison with the O type group (92.9 vs. 67.3%; p<0.05). Conclusions: Our results suggest that the occurrence of IS is more frequent among patients of the AB blood type.
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series Arquivos de Neuro-Psiquiatria
spelling doaj-art-ab93da97b36a482bb0069418584acd952025-08-20T02:20:12ZengThieme Revinter PublicaçõesArquivos de Neuro-Psiquiatria1678-422710.1590/0004-282x-anp-2020-0219ABO blood group system and occurrence of ischemic strokeRafaella Chiodini LOTZCarolina da Silveira WELTERSilvia Aparecida RAMOSLeslie Ecker FERREIRANorberto Luiz CABRALPaulo Henrique Condeixa de FRANÇAABSTRACT Background: Ischemic stroke (IS) is a multifactorial disease that presents high rates of morbimortality in Brazil. Several studies proved that there is a link between the ABO blood group system and the occurrence of thrombotic events. Nonetheless, its association with IS is not well established. Objective: For that reason, the purpose hereof was to investigate the relation between the ABO blood groups and the occurrence of IS in a Brazilian cohort of cerebrovascular diseases. Methods: Five hundred and twenty-nine subjects were included over 12 months, from which 275 presented an IS episode and 254 composed the control group. Blood samples were drawn for direct and reverse serotyping. The control and IS groups were compared regarding the traditional risk factors and the distribution of the ABO blood groups. Results: The IS group presented a higher prevalence of systemic arterial hypertension (SAH), diabetes mellitus, smoking habits, family history, cardiopathy, and sedentary lifestyle in comparison with the control group. The AB blood type prevailed among the patients (5.1 vs. 1.6%; p<0.05) and this group had more SAH cases in comparison with the O type group (92.9 vs. 67.3%; p<0.05). Conclusions: Our results suggest that the occurrence of IS is more frequent among patients of the AB blood type.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2021005024101&tlng=enIschemic StrokeABO Blood-Group SystemRisk Factors
spellingShingle Rafaella Chiodini LOTZ
Carolina da Silveira WELTER
Silvia Aparecida RAMOS
Leslie Ecker FERREIRA
Norberto Luiz CABRAL
Paulo Henrique Condeixa de FRANÇA
ABO blood group system and occurrence of ischemic stroke
Arquivos de Neuro-Psiquiatria
Ischemic Stroke
ABO Blood-Group System
Risk Factors
title ABO blood group system and occurrence of ischemic stroke
title_full ABO blood group system and occurrence of ischemic stroke
title_fullStr ABO blood group system and occurrence of ischemic stroke
title_full_unstemmed ABO blood group system and occurrence of ischemic stroke
title_short ABO blood group system and occurrence of ischemic stroke
title_sort abo blood group system and occurrence of ischemic stroke
topic Ischemic Stroke
ABO Blood-Group System
Risk Factors
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2021005024101&tlng=en
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AT leslieeckerferreira abobloodgroupsystemandoccurrenceofischemicstroke
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