Lupus-Associated Pulmonary Arterial Hypertension: Variable Course and Importance of Prompt Recognition
We describe a critically ill young woman with systemic lupus erythematosus (SLE) presenting with circulatory shock, multiorgan dysfunction, and elevated right-sided heart pressures. She was found to have recurrent acute severe pulmonary arterial hypertension (PAH) in the setting of an SLE flare. Our...
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| Format: | Article |
| Language: | English |
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Wiley
2015-01-01
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| Series: | Case Reports in Medicine |
| Online Access: | http://dx.doi.org/10.1155/2015/328435 |
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| author | Kofi A. Mensah Rajwardhan Yadav Terence K. Trow Cristina M. Brunet Wassim H. Fares |
| author_facet | Kofi A. Mensah Rajwardhan Yadav Terence K. Trow Cristina M. Brunet Wassim H. Fares |
| author_sort | Kofi A. Mensah |
| collection | DOAJ |
| description | We describe a critically ill young woman with systemic lupus erythematosus (SLE) presenting with circulatory shock, multiorgan dysfunction, and elevated right-sided heart pressures. She was found to have recurrent acute severe pulmonary arterial hypertension (PAH) in the setting of an SLE flare. Our report highlights the variable course that SLE-associated PAH can take in the same patient and the implications of this for instituting the most effective treatment approach with each episode. This report also highlights the potential for SLE-associated PAH to present with life-threatening symptoms requiring critical care level interventions. We also describe evidence-based therapies, which can result in significant improvement in symptoms, function, and long-term outcomes. |
| format | Article |
| id | doaj-art-ab8e7e85ddb94e24bbc9942b29e58493 |
| institution | OA Journals |
| issn | 1687-9627 1687-9635 |
| language | English |
| publishDate | 2015-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Medicine |
| spelling | doaj-art-ab8e7e85ddb94e24bbc9942b29e584932025-08-20T02:20:13ZengWileyCase Reports in Medicine1687-96271687-96352015-01-01201510.1155/2015/328435328435Lupus-Associated Pulmonary Arterial Hypertension: Variable Course and Importance of Prompt RecognitionKofi A. Mensah0Rajwardhan Yadav1Terence K. Trow2Cristina M. Brunet3Wassim H. Fares4Section of Rheumatology, Department of Internal Medicine, Yale University School of Medicine, 333 Cedar Street, New Haven, CT 06510, USASection of Rheumatology, Department of Internal Medicine, Yale University School of Medicine, 333 Cedar Street, New Haven, CT 06510, USASection of Pulmonary, Critical Care and Sleep Medicine, Department of Internal Medicine, Yale University School of Medicine, 333 Cedar Street, New Haven, CT 06510, USASection of Rheumatology, Department of Internal Medicine, Yale University School of Medicine, 333 Cedar Street, New Haven, CT 06510, USASection of Pulmonary, Critical Care and Sleep Medicine, Department of Internal Medicine, Yale University School of Medicine, 333 Cedar Street, New Haven, CT 06510, USAWe describe a critically ill young woman with systemic lupus erythematosus (SLE) presenting with circulatory shock, multiorgan dysfunction, and elevated right-sided heart pressures. She was found to have recurrent acute severe pulmonary arterial hypertension (PAH) in the setting of an SLE flare. Our report highlights the variable course that SLE-associated PAH can take in the same patient and the implications of this for instituting the most effective treatment approach with each episode. This report also highlights the potential for SLE-associated PAH to present with life-threatening symptoms requiring critical care level interventions. We also describe evidence-based therapies, which can result in significant improvement in symptoms, function, and long-term outcomes.http://dx.doi.org/10.1155/2015/328435 |
| spellingShingle | Kofi A. Mensah Rajwardhan Yadav Terence K. Trow Cristina M. Brunet Wassim H. Fares Lupus-Associated Pulmonary Arterial Hypertension: Variable Course and Importance of Prompt Recognition Case Reports in Medicine |
| title | Lupus-Associated Pulmonary Arterial Hypertension: Variable Course and Importance of Prompt Recognition |
| title_full | Lupus-Associated Pulmonary Arterial Hypertension: Variable Course and Importance of Prompt Recognition |
| title_fullStr | Lupus-Associated Pulmonary Arterial Hypertension: Variable Course and Importance of Prompt Recognition |
| title_full_unstemmed | Lupus-Associated Pulmonary Arterial Hypertension: Variable Course and Importance of Prompt Recognition |
| title_short | Lupus-Associated Pulmonary Arterial Hypertension: Variable Course and Importance of Prompt Recognition |
| title_sort | lupus associated pulmonary arterial hypertension variable course and importance of prompt recognition |
| url | http://dx.doi.org/10.1155/2015/328435 |
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