Evaluation of a flow cytometry-based surrogate assay (FlowSA) for the detection of SARS-CoV-2 in clinical samples

Evaluation of a flow cytometry-based surrogate assay (FlowSA) for the detection of SARS-CoV-2 in clinical samples

Introduction: The current diagnostic methods for SARS-CoV-2 rely on quantitative RT-PCR. However, the presence of viral RNA in samples does not necessarily reflect the presence of an infectious virus. Therefore, the reliable detection of infectious SARS-CoV-2 in clinical samples is necessary to limi...

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Bibliographic Details
Main Authors: Vinit Upasani, Marjolein Knoester, Daniele Pantano, Lili Gard, Jolanda M. Smit, Bernardina T.F. van der Gun, Adriana Tami, Izabela A. Rodenhuis-Zybert
Format: Article
Language:English
Published: Elsevier 2025-02-01
Series:Journal of Clinical Virology Plus
Subjects:
SARS-CoV-2
Flow cytometry-based surrogate assay
Nucleocapsid
RT-PCR
Cytopathic effect
Online Access:http://www.sciencedirect.com/science/article/pii/S2667038025000031
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