Evidences of a New Psychobiotic Formulation on Body Composition and Anxiety
Background. Gut microbiota is implied in obesity, because of its ability to harvest energy from diet, and in the regulation of behavior. Given the link between gut microbiota, body composition, obesity, and anxiety, the aim of this study was to evaluate the effects of a new psychobiotic formulation....
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| Format: | Article |
| Language: | English |
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Wiley
2017-01-01
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| Series: | Mediators of Inflammation |
| Online Access: | http://dx.doi.org/10.1155/2017/5650627 |
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| author | Carmela Colica Ennio Avolio Patrizio Bollero Renata Costa de Miranda Simona Ferraro Paola Sinibaldi Salimei Antonino De Lorenzo Laura Di Renzo |
| author_facet | Carmela Colica Ennio Avolio Patrizio Bollero Renata Costa de Miranda Simona Ferraro Paola Sinibaldi Salimei Antonino De Lorenzo Laura Di Renzo |
| author_sort | Carmela Colica |
| collection | DOAJ |
| description | Background. Gut microbiota is implied in obesity, because of its ability to harvest energy from diet, and in the regulation of behavior. Given the link between gut microbiota, body composition, obesity, and anxiety, the aim of this study was to evaluate the effects of a new psychobiotic formulation. Methods. Eligible patients were randomly divided into three groups: psychobiotics oral suspension group (POSG); dietary treatment group (DTG); combined treatment group (CTG). All subjects underwent body composition and psychological profile evaluation. Results. Significant changes in body composition parameters in each group were relieved after all treatments. Hamilton anxiety rating scale (HAM-A) highlighted a significant reduction of the total score for all study population after treatments in POSG (p=0.01) and CTG (p=0.04). A reduction of HAM-A total score in anxious subjects in POSG or CTG and a significant reduction of positive subjects for HAM-A in POSG (p=0.03) and in CDG (p=0.01) were shown. Discussion. Three-week intake of selected POS represents a good approach to solve problems related to obesity and behavior disorders. However, new clinical trials need to be performed on a larger population and for a longer period of treatment before definitive conclusions can be made. This trial is registered with NCT01890070. |
| format | Article |
| id | doaj-art-ab85f2f9bcd0499d93922aa9cbab5ef5 |
| institution | OA Journals |
| issn | 0962-9351 1466-1861 |
| language | English |
| publishDate | 2017-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Mediators of Inflammation |
| spelling | doaj-art-ab85f2f9bcd0499d93922aa9cbab5ef52025-08-20T02:20:13ZengWileyMediators of Inflammation0962-93511466-18612017-01-01201710.1155/2017/56506275650627Evidences of a New Psychobiotic Formulation on Body Composition and AnxietyCarmela Colica0Ennio Avolio1Patrizio Bollero2Renata Costa de Miranda3Simona Ferraro4Paola Sinibaldi Salimei5Antonino De Lorenzo6Laura Di Renzo7CNR, IBFM UOS of Germaneto, University “Magna Graecia” of Catanzaro, Campus “Salvatore Venuta”, Germaneto, 88100 Catanzaro, ItalyComparative Neuroanatomy Laboratory of Ecology Department, University of Calabria, Ponte Pietro Bucci, Arcavacata di Rende, 87030 Cosenza, ItalyDepartment of Systems Medicine, University of Rome Tor Vergata, Via Montpellier 1, 00133 Rome, ItalyPhD School of Medical-Surgical Applied Sciences, University of Rome Tor Vergata, Via Montpellier 1, 00133 Rome, ItalyHealth Center Srl, Biomedical and Nutritional Center, 87100 Cosenza, ItalySection of Clinical Nutrition and Nutrigenomic, Department of Biomedicine and Prevention, University of Rome Tor Vergata, Via Montpellier 1, 00133 Rome, ItalySection of Clinical Nutrition and Nutrigenomic, Department of Biomedicine and Prevention, University of Rome Tor Vergata, Via Montpellier 1, 00133 Rome, ItalySection of Clinical Nutrition and Nutrigenomic, Department of Biomedicine and Prevention, University of Rome Tor Vergata, Via Montpellier 1, 00133 Rome, ItalyBackground. Gut microbiota is implied in obesity, because of its ability to harvest energy from diet, and in the regulation of behavior. Given the link between gut microbiota, body composition, obesity, and anxiety, the aim of this study was to evaluate the effects of a new psychobiotic formulation. Methods. Eligible patients were randomly divided into three groups: psychobiotics oral suspension group (POSG); dietary treatment group (DTG); combined treatment group (CTG). All subjects underwent body composition and psychological profile evaluation. Results. Significant changes in body composition parameters in each group were relieved after all treatments. Hamilton anxiety rating scale (HAM-A) highlighted a significant reduction of the total score for all study population after treatments in POSG (p=0.01) and CTG (p=0.04). A reduction of HAM-A total score in anxious subjects in POSG or CTG and a significant reduction of positive subjects for HAM-A in POSG (p=0.03) and in CDG (p=0.01) were shown. Discussion. Three-week intake of selected POS represents a good approach to solve problems related to obesity and behavior disorders. However, new clinical trials need to be performed on a larger population and for a longer period of treatment before definitive conclusions can be made. This trial is registered with NCT01890070.http://dx.doi.org/10.1155/2017/5650627 |
| spellingShingle | Carmela Colica Ennio Avolio Patrizio Bollero Renata Costa de Miranda Simona Ferraro Paola Sinibaldi Salimei Antonino De Lorenzo Laura Di Renzo Evidences of a New Psychobiotic Formulation on Body Composition and Anxiety Mediators of Inflammation |
| title | Evidences of a New Psychobiotic Formulation on Body Composition and Anxiety |
| title_full | Evidences of a New Psychobiotic Formulation on Body Composition and Anxiety |
| title_fullStr | Evidences of a New Psychobiotic Formulation on Body Composition and Anxiety |
| title_full_unstemmed | Evidences of a New Psychobiotic Formulation on Body Composition and Anxiety |
| title_short | Evidences of a New Psychobiotic Formulation on Body Composition and Anxiety |
| title_sort | evidences of a new psychobiotic formulation on body composition and anxiety |
| url | http://dx.doi.org/10.1155/2017/5650627 |
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