Toxicity Evaluation of a Novel Magnetic Resonance Imaging Marker, CoCl2-N-Acetylcysteine, in Rats

Toxicity Evaluation of a Novel Magnetic Resonance Imaging Marker, CoCl2-N-Acetylcysteine, in Rats

C4 (cobalt dichloride-N-acetylcysteine [1% CoCl2:2% NAC]) is a novel magnetic resonance imaging contrast marker that facilitates visualization of implanted radioactive seeds in cancer brachytherapy. We evaluated the toxicity of C4. Rats were assigned to control (0% CoCl2:NAC), low-dose (0.1% CoCl2:2...

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Bibliographic Details
Main Authors: Li Wang, Mihai Gagea, Karen Martirosyan, Mary Johansen, Timothy Madden, Lisa Norberg, Kirk S. Culotta, Steven J. Frank
Format: Article
Language:English
Published: Wiley 2018-01-01
Series:Journal of Toxicology
Online Access:http://dx.doi.org/10.1155/2018/9173452
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