Targeted Lung Premetastasis Niche: Mechanisms, Strategies, and Application

Targeted Lung Premetastasis Niche: Mechanisms, Strategies, and Application

ABSTRACT Lung metastasis remains a leading cause of cancer mortality, driven not only by primary tumors but crucially by dynamic interactions within the premetastatic niche (PMN). Emerging evidence reveals that organ‐specific PMN formation precedes tumor cell arrival, creating an immunosuppressive m...

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Bibliographic Details
Main Authors: Chenghao Cao, Di Lu, Huigang Li, Shen Pan, Jianyong Zhuo, Zuyuan Lin, Chiyu He, Peiru Zhang, Songmin Ying, Xuyong Wei, Shusen Zheng, Zhe Yang, Xiao Xu
Format: Article
Language:English
Published: Wiley 2025-06-01
Series:MedComm
Subjects:
clinical implication
lung metastasis
premetastatic niche
therapeutic strategy
tumor microenvironment
Online Access:https://doi.org/10.1002/mco2.70248
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