Chromosomal Aneuploidy Affects the Global Proteome Equilibrium of Colorectal Cancer Cells

Background: Chromosomal aneuploidy has been identified as a prognostic factor in the majority of sporadic carcinomas. However, it is not known how chromosomal aneuploidy affects chromosome-specific protein expression in particular, and the cellular proteome equilibrium in general.

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Main Authors: Timo Gemoll, Jens K. Habermann, Susanne Becker, Silke Szymczak, Madhvi B. Upender, Hans-Peter Bruch, Ulf Hellman, Thomas Ried, Gert Auer, Hans Jörnvall, Uwe J. Roblick
Format: Article
Language:English
Published: Wiley 2013-01-01
Series:Analytical Cellular Pathology
Online Access:http://dx.doi.org/10.3233/ACP-140088
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author Timo Gemoll
Jens K. Habermann
Susanne Becker
Silke Szymczak
Madhvi B. Upender
Hans-Peter Bruch
Ulf Hellman
Thomas Ried
Gert Auer
Hans Jörnvall
Uwe J. Roblick
author_facet Timo Gemoll
Jens K. Habermann
Susanne Becker
Silke Szymczak
Madhvi B. Upender
Hans-Peter Bruch
Ulf Hellman
Thomas Ried
Gert Auer
Hans Jörnvall
Uwe J. Roblick
author_sort Timo Gemoll
collection DOAJ
description Background: Chromosomal aneuploidy has been identified as a prognostic factor in the majority of sporadic carcinomas. However, it is not known how chromosomal aneuploidy affects chromosome-specific protein expression in particular, and the cellular proteome equilibrium in general.
format Article
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institution Kabale University
issn 2210-7177
2210-7185
language English
publishDate 2013-01-01
publisher Wiley
record_format Article
series Analytical Cellular Pathology
spelling doaj-art-ab6657c143e745e69e01cc041fb890592025-02-03T05:47:20ZengWileyAnalytical Cellular Pathology2210-71772210-71852013-01-01365-614916110.3233/ACP-140088Chromosomal Aneuploidy Affects the Global Proteome Equilibrium of Colorectal Cancer CellsTimo Gemoll0Jens K. Habermann1Susanne Becker2Silke Szymczak3Madhvi B. Upender4Hans-Peter Bruch5Ulf Hellman6Thomas Ried7Gert Auer8Hans Jörnvall9Uwe J. Roblick10Section for Translational Surgical Oncology & Biobanking, Department of Surgery, University of Lübeck, Lübeck, GermanySection for Translational Surgical Oncology & Biobanking, Department of Surgery, University of Lübeck, Lübeck, GermanyKarolinska Biomic Center, Karolinska Institutet, Stockholm, SwedenInstitute of Medical Biometry and Statistics, University of Lübeck, Lübeck, GermanyCenter for Cancer Research, National Cancer Institute, NIH, Bethesda, MD, USASection for Translational Surgical Oncology & Biobanking, Department of Surgery, University of Lübeck, Lübeck, GermanyLudwig Institute for Cancer Research, Ltd. Uppsala, Uppsala, SwedenCenter for Cancer Research, National Cancer Institute, NIH, Bethesda, MD, USAKarolinska Biomic Center, Karolinska Institutet, Stockholm, SwedenDepartment of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, SwedenSection for Translational Surgical Oncology & Biobanking, Department of Surgery, University of Lübeck, Lübeck, GermanyBackground: Chromosomal aneuploidy has been identified as a prognostic factor in the majority of sporadic carcinomas. However, it is not known how chromosomal aneuploidy affects chromosome-specific protein expression in particular, and the cellular proteome equilibrium in general.http://dx.doi.org/10.3233/ACP-140088
spellingShingle Timo Gemoll
Jens K. Habermann
Susanne Becker
Silke Szymczak
Madhvi B. Upender
Hans-Peter Bruch
Ulf Hellman
Thomas Ried
Gert Auer
Hans Jörnvall
Uwe J. Roblick
Chromosomal Aneuploidy Affects the Global Proteome Equilibrium of Colorectal Cancer Cells
Analytical Cellular Pathology
title Chromosomal Aneuploidy Affects the Global Proteome Equilibrium of Colorectal Cancer Cells
title_full Chromosomal Aneuploidy Affects the Global Proteome Equilibrium of Colorectal Cancer Cells
title_fullStr Chromosomal Aneuploidy Affects the Global Proteome Equilibrium of Colorectal Cancer Cells
title_full_unstemmed Chromosomal Aneuploidy Affects the Global Proteome Equilibrium of Colorectal Cancer Cells
title_short Chromosomal Aneuploidy Affects the Global Proteome Equilibrium of Colorectal Cancer Cells
title_sort chromosomal aneuploidy affects the global proteome equilibrium of colorectal cancer cells
url http://dx.doi.org/10.3233/ACP-140088
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