Clinical exploration of allogeneic PRP in refractory wound
[Objective] To explore the possibility of performing allogeneic platelet-rich plasma (PRP) treatment for patients who were not suitable for autologous PRP collection through case reports of two patients with refractory wounds treated with allogeneic PRP. [Methods] The ABO-compatible allogeneic whole...
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| Format: | Article |
| Language: | zho |
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Institute of Blood Transfusion of Chinese Academy of Medical Sciences
2025-05-01
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| Series: | Zhongguo shuxue zazhi |
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| Online Access: | https://www.cjbt.cn/thesisDetails#10.13303/j.cjbt.issn.1004-549x.2025.05.021&lang=en |
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| author | TAN Qiang WU Ling LIU Liping GAN Xinyu PENG Tao |
| author_facet | TAN Qiang WU Ling LIU Liping GAN Xinyu PENG Tao |
| author_sort | TAN Qiang |
| collection | DOAJ |
| description | [Objective] To explore the possibility of performing allogeneic platelet-rich plasma (PRP) treatment for patients who were not suitable for autologous PRP collection through case reports of two patients with refractory wounds treated with allogeneic PRP. [Methods] The ABO-compatible allogeneic whole blood was centrifuged 3 times to obtain allogeneic PRP within 6 hours of blood collection. Then the qualified allogeneic PRP was applied to 2 cases of refractory wound on the same day. [Results] The platelet concentration in allogeneic PRP was higher than 1 000×109/L, and the test results of infectious diseases, as well as the mixing of red blood cells and white blood cells, met the standard of quality control. Both patients achieved satisfactory wound healing outcomes (3 d). [Conclusions] For patients who were not suitable for autologous PRP treatment, allogeneic PRP might be a new option. |
| format | Article |
| id | doaj-art-ab60dff4bea64ca1b2732b859cd43c31 |
| institution | OA Journals |
| issn | 1004-549X |
| language | zho |
| publishDate | 2025-05-01 |
| publisher | Institute of Blood Transfusion of Chinese Academy of Medical Sciences |
| record_format | Article |
| series | Zhongguo shuxue zazhi |
| spelling | doaj-art-ab60dff4bea64ca1b2732b859cd43c312025-08-20T01:57:15ZzhoInstitute of Blood Transfusion of Chinese Academy of Medical SciencesZhongguo shuxue zazhi1004-549X2025-05-0138573473810.13303/j.cjbt.issn.1004-549x.2025.05.0211004-549X(2025)5-0734-05Clinical exploration of allogeneic PRP in refractory woundTAN Qiang0WU Ling1LIU Liping2GAN Xinyu3PENG Tao4Department of Blood Transfusion, the General Hospital of Western Theater Command, Chengdu 610036, ChinaDepartment of Blood Transfusion, the General Hospital of Western Theater Command, Chengdu 610036, ChinaDepartment of Blood Transfusion, the General Hospital of Western Theater Command, Chengdu 610036, ChinaDepartment of Blood Transfusion, the General Hospital of Western Theater Command, Chengdu 610036, ChinaDepartment of Blood Transfusion, the General Hospital of Western Theater Command, Chengdu 610036, China[Objective] To explore the possibility of performing allogeneic platelet-rich plasma (PRP) treatment for patients who were not suitable for autologous PRP collection through case reports of two patients with refractory wounds treated with allogeneic PRP. [Methods] The ABO-compatible allogeneic whole blood was centrifuged 3 times to obtain allogeneic PRP within 6 hours of blood collection. Then the qualified allogeneic PRP was applied to 2 cases of refractory wound on the same day. [Results] The platelet concentration in allogeneic PRP was higher than 1 000×109/L, and the test results of infectious diseases, as well as the mixing of red blood cells and white blood cells, met the standard of quality control. Both patients achieved satisfactory wound healing outcomes (3 d). [Conclusions] For patients who were not suitable for autologous PRP treatment, allogeneic PRP might be a new option.https://www.cjbt.cn/thesisDetails#10.13303/j.cjbt.issn.1004-549x.2025.05.021&lang=enplatelet-rich plasma (prp)allogeneic prpwound treatment |
| spellingShingle | TAN Qiang WU Ling LIU Liping GAN Xinyu PENG Tao Clinical exploration of allogeneic PRP in refractory wound Zhongguo shuxue zazhi platelet-rich plasma (prp) allogeneic prp wound treatment |
| title | Clinical exploration of allogeneic PRP in refractory wound |
| title_full | Clinical exploration of allogeneic PRP in refractory wound |
| title_fullStr | Clinical exploration of allogeneic PRP in refractory wound |
| title_full_unstemmed | Clinical exploration of allogeneic PRP in refractory wound |
| title_short | Clinical exploration of allogeneic PRP in refractory wound |
| title_sort | clinical exploration of allogeneic prp in refractory wound |
| topic | platelet-rich plasma (prp) allogeneic prp wound treatment |
| url | https://www.cjbt.cn/thesisDetails#10.13303/j.cjbt.issn.1004-549x.2025.05.021&lang=en |
| work_keys_str_mv | AT tanqiang clinicalexplorationofallogeneicprpinrefractorywound AT wuling clinicalexplorationofallogeneicprpinrefractorywound AT liuliping clinicalexplorationofallogeneicprpinrefractorywound AT ganxinyu clinicalexplorationofallogeneicprpinrefractorywound AT pengtao clinicalexplorationofallogeneicprpinrefractorywound |