Mechanochemical activation of 2D MnPS3 for sub-attomolar sensing

Abstract Molecular detection is important in biosensing, food safety, and environmental surveillance. The high biocompatibility, superior mechanical stability, and low cost make plasmon-free surface-enhanced Raman scattering (SERS) a promising sensing technique, the ultrahigh sensitivity of which is...

Full description

Saved in:
Bibliographic Details
Main Authors: Wenjun Chen, Jiabao Gui, Xiangchao Weng, Junyang Tan, Junhua Huang, Zhiqiang Lin, Benli Zhao, Lang-Hong Wang, Xin-An Zeng, Changjiu Teng, Shilong Zhao, Baofu Ding, Bilu Liu, Hui-Ming Cheng
Format: Article
Language:English
Published: Nature Portfolio 2024-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-54608-0
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1850216038800556032
author Wenjun Chen
Jiabao Gui
Xiangchao Weng
Junyang Tan
Junhua Huang
Zhiqiang Lin
Benli Zhao
Lang-Hong Wang
Xin-An Zeng
Changjiu Teng
Shilong Zhao
Baofu Ding
Bilu Liu
Hui-Ming Cheng
author_facet Wenjun Chen
Jiabao Gui
Xiangchao Weng
Junyang Tan
Junhua Huang
Zhiqiang Lin
Benli Zhao
Lang-Hong Wang
Xin-An Zeng
Changjiu Teng
Shilong Zhao
Baofu Ding
Bilu Liu
Hui-Ming Cheng
author_sort Wenjun Chen
collection DOAJ
description Abstract Molecular detection is important in biosensing, food safety, and environmental surveillance. The high biocompatibility, superior mechanical stability, and low cost make plasmon-free surface-enhanced Raman scattering (SERS) a promising sensing technique, the ultrahigh sensitivity of which is urgently pursued for realistic applications. As a proof of concept, we report a mechanochemical strategy, which combines the wrinkling and chemical functionalization, to fabricate a plasmon-free SERS platform based on 2D MnPS3 with a sub-attomolar detection limit. In detail, the formation of wrinkles in 2D MnPS3 enables a SERS substrate of the material to detect trace methylene blue molecules. The mechanism is experimentally revealed that the wrinkled structures contribute to the improvement of light-matter coupling. On this basis, decorating a wrinkled MnPS3 which has absorbed methylene blue with histamine dihydrochloride further lowers the detection limit to 10−19 M. Because the amino groups in histamine dihydrochloride molecules are crosslinkers that create more pathways to promote charge transfer between these substances. This work provides a guidance for the design of SERS sensors with single-molecule-level sensitivity.
format Article
id doaj-art-ab5e0f31257e4ff88c7cd35c74fe4606
institution OA Journals
issn 2041-1723
language English
publishDate 2024-11-01
publisher Nature Portfolio
record_format Article
series Nature Communications
spelling doaj-art-ab5e0f31257e4ff88c7cd35c74fe46062025-08-20T02:08:26ZengNature PortfolioNature Communications2041-17232024-11-011511910.1038/s41467-024-54608-0Mechanochemical activation of 2D MnPS3 for sub-attomolar sensingWenjun Chen0Jiabao Gui1Xiangchao Weng2Junyang Tan3Junhua Huang4Zhiqiang Lin5Benli Zhao6Lang-Hong Wang7Xin-An Zeng8Changjiu Teng9Shilong Zhao10Baofu Ding11Bilu Liu12Hui-Ming Cheng13School of Electronic Information Engineering, Foshan UniversitySchool of Electronic Information Engineering, Foshan UniversitySchool of Electronic Information Engineering, Foshan UniversityShenzhen Geim Graphene Center, Tsinghua-Berkeley Shenzhen Institute and Institute of Materials Research, Tsinghua Shenzhen International Graduate School, Tsinghua UniversityState Key Laboratory of Optoelectronic Materials and Technologies, School of Electronics and Information Technology, Sun Yat-Sen UniversityNational Key Laboratory of Materials for Integrated Circuits, Shenzhen Institute of Advanced Electronic Materials, Shenzhen Institute of Advanced Technology, Chinese Academy of SciencesFoshan Stomatology Hospital & School of Medicine, Foshan UniversitySchool of Food Science and Engineering, Guangdong Provincial Key Laboratory of Intelligent Food Manufacturing, Foshan UniversitySchool of Food Science and Engineering, Guangdong Provincial Key Laboratory of Intelligent Food Manufacturing, Foshan UniversitySchool of Electronic Information Engineering, Foshan UniversitySchool of Electronic Information Engineering, Foshan UniversityFaculty of Materials Science and Energy Engineering/Institute of Technology for Carbon Neutrality, Shenzhen Institute of Advanced Technology, Chinese Academy of SciencesShenzhen Geim Graphene Center, Tsinghua-Berkeley Shenzhen Institute and Institute of Materials Research, Tsinghua Shenzhen International Graduate School, Tsinghua UniversityFaculty of Materials Science and Energy Engineering/Institute of Technology for Carbon Neutrality, Shenzhen Institute of Advanced Technology, Chinese Academy of SciencesAbstract Molecular detection is important in biosensing, food safety, and environmental surveillance. The high biocompatibility, superior mechanical stability, and low cost make plasmon-free surface-enhanced Raman scattering (SERS) a promising sensing technique, the ultrahigh sensitivity of which is urgently pursued for realistic applications. As a proof of concept, we report a mechanochemical strategy, which combines the wrinkling and chemical functionalization, to fabricate a plasmon-free SERS platform based on 2D MnPS3 with a sub-attomolar detection limit. In detail, the formation of wrinkles in 2D MnPS3 enables a SERS substrate of the material to detect trace methylene blue molecules. The mechanism is experimentally revealed that the wrinkled structures contribute to the improvement of light-matter coupling. On this basis, decorating a wrinkled MnPS3 which has absorbed methylene blue with histamine dihydrochloride further lowers the detection limit to 10−19 M. Because the amino groups in histamine dihydrochloride molecules are crosslinkers that create more pathways to promote charge transfer between these substances. This work provides a guidance for the design of SERS sensors with single-molecule-level sensitivity.https://doi.org/10.1038/s41467-024-54608-0
spellingShingle Wenjun Chen
Jiabao Gui
Xiangchao Weng
Junyang Tan
Junhua Huang
Zhiqiang Lin
Benli Zhao
Lang-Hong Wang
Xin-An Zeng
Changjiu Teng
Shilong Zhao
Baofu Ding
Bilu Liu
Hui-Ming Cheng
Mechanochemical activation of 2D MnPS3 for sub-attomolar sensing
Nature Communications
title Mechanochemical activation of 2D MnPS3 for sub-attomolar sensing
title_full Mechanochemical activation of 2D MnPS3 for sub-attomolar sensing
title_fullStr Mechanochemical activation of 2D MnPS3 for sub-attomolar sensing
title_full_unstemmed Mechanochemical activation of 2D MnPS3 for sub-attomolar sensing
title_short Mechanochemical activation of 2D MnPS3 for sub-attomolar sensing
title_sort mechanochemical activation of 2d mnps3 for sub attomolar sensing
url https://doi.org/10.1038/s41467-024-54608-0
work_keys_str_mv AT wenjunchen mechanochemicalactivationof2dmnps3forsubattomolarsensing
AT jiabaogui mechanochemicalactivationof2dmnps3forsubattomolarsensing
AT xiangchaoweng mechanochemicalactivationof2dmnps3forsubattomolarsensing
AT junyangtan mechanochemicalactivationof2dmnps3forsubattomolarsensing
AT junhuahuang mechanochemicalactivationof2dmnps3forsubattomolarsensing
AT zhiqianglin mechanochemicalactivationof2dmnps3forsubattomolarsensing
AT benlizhao mechanochemicalactivationof2dmnps3forsubattomolarsensing
AT langhongwang mechanochemicalactivationof2dmnps3forsubattomolarsensing
AT xinanzeng mechanochemicalactivationof2dmnps3forsubattomolarsensing
AT changjiuteng mechanochemicalactivationof2dmnps3forsubattomolarsensing
AT shilongzhao mechanochemicalactivationof2dmnps3forsubattomolarsensing
AT baofuding mechanochemicalactivationof2dmnps3forsubattomolarsensing
AT biluliu mechanochemicalactivationof2dmnps3forsubattomolarsensing
AT huimingcheng mechanochemicalactivationof2dmnps3forsubattomolarsensing