Retreatment with Bendamustine-Bortezomib-Dexamethasone in a Patient with Relapsed/Refractory Multiple Myeloma

The clinical management of relapsed/refractory multiple myeloma and the correct choice of the most suitable therapy in heavily pretreated and fragile patients are tough clinical issues for clinicians. In advanced phases of disease, the choice of available therapies becomes very poor, and the retreat...

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Main Authors: Claudio Cerchione, Davide Nappi, Maria Di Perna, Irene Zacheo, Anna Emanuele Pareto, Marco Picardi, Lucio Catalano, Fabrizio Pane
Format: Article
Language:English
Published: Wiley 2016-01-01
Series:Case Reports in Hematology
Online Access:http://dx.doi.org/10.1155/2016/6745286
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author Claudio Cerchione
Davide Nappi
Maria Di Perna
Irene Zacheo
Anna Emanuele Pareto
Marco Picardi
Lucio Catalano
Fabrizio Pane
author_facet Claudio Cerchione
Davide Nappi
Maria Di Perna
Irene Zacheo
Anna Emanuele Pareto
Marco Picardi
Lucio Catalano
Fabrizio Pane
author_sort Claudio Cerchione
collection DOAJ
description The clinical management of relapsed/refractory multiple myeloma and the correct choice of the most suitable therapy in heavily pretreated and fragile patients are tough clinical issues for clinicians. In advanced phases of disease, the choice of available therapies becomes very poor, and the retreatment with previously adopted and effective therapy, although unpredictable, could be an effective option. In this report, we describe the clinical history of a patient, previously treated with 9 lines of therapy, refractory to bortezomib and IMIDs, for whom the retreatment with bendamustine resulted in a stable disease with good quality of life.
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issn 2090-6560
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publishDate 2016-01-01
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series Case Reports in Hematology
spelling doaj-art-ab51cd43838f4f29842bdcf98d34712e2025-02-03T01:02:30ZengWileyCase Reports in Hematology2090-65602090-65792016-01-01201610.1155/2016/67452866745286Retreatment with Bendamustine-Bortezomib-Dexamethasone in a Patient with Relapsed/Refractory Multiple MyelomaClaudio Cerchione0Davide Nappi1Maria Di Perna2Irene Zacheo3Anna Emanuele Pareto4Marco Picardi5Lucio Catalano6Fabrizio Pane7Hematology, University Federico II, Via Pansini 5, 80131 Napoli, ItalyHematology, University Federico II, Via Pansini 5, 80131 Napoli, ItalyHematology, University Federico II, Via Pansini 5, 80131 Napoli, ItalyHematology, University Federico II, Via Pansini 5, 80131 Napoli, ItalyHematology, University Federico II, Via Pansini 5, 80131 Napoli, ItalyHematology, University Federico II, Via Pansini 5, 80131 Napoli, ItalyHematology, University Federico II, Via Pansini 5, 80131 Napoli, ItalyHematology, University Federico II, Via Pansini 5, 80131 Napoli, ItalyThe clinical management of relapsed/refractory multiple myeloma and the correct choice of the most suitable therapy in heavily pretreated and fragile patients are tough clinical issues for clinicians. In advanced phases of disease, the choice of available therapies becomes very poor, and the retreatment with previously adopted and effective therapy, although unpredictable, could be an effective option. In this report, we describe the clinical history of a patient, previously treated with 9 lines of therapy, refractory to bortezomib and IMIDs, for whom the retreatment with bendamustine resulted in a stable disease with good quality of life.http://dx.doi.org/10.1155/2016/6745286
spellingShingle Claudio Cerchione
Davide Nappi
Maria Di Perna
Irene Zacheo
Anna Emanuele Pareto
Marco Picardi
Lucio Catalano
Fabrizio Pane
Retreatment with Bendamustine-Bortezomib-Dexamethasone in a Patient with Relapsed/Refractory Multiple Myeloma
Case Reports in Hematology
title Retreatment with Bendamustine-Bortezomib-Dexamethasone in a Patient with Relapsed/Refractory Multiple Myeloma
title_full Retreatment with Bendamustine-Bortezomib-Dexamethasone in a Patient with Relapsed/Refractory Multiple Myeloma
title_fullStr Retreatment with Bendamustine-Bortezomib-Dexamethasone in a Patient with Relapsed/Refractory Multiple Myeloma
title_full_unstemmed Retreatment with Bendamustine-Bortezomib-Dexamethasone in a Patient with Relapsed/Refractory Multiple Myeloma
title_short Retreatment with Bendamustine-Bortezomib-Dexamethasone in a Patient with Relapsed/Refractory Multiple Myeloma
title_sort retreatment with bendamustine bortezomib dexamethasone in a patient with relapsed refractory multiple myeloma
url http://dx.doi.org/10.1155/2016/6745286
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