T follicular helper cell is essential for M2 macrophage polarization and pulmonary vascular remodeling in hypoxia-induced pulmonary hypertension

T follicular helper cell is essential for M2 macrophage polarization and pulmonary vascular remodeling in hypoxia-induced pulmonary hypertension

Abstract Background Hypoxia-induced pulmonary hypertension (HPH) is a subgroup of type 3 pulmonary hypertension that may cause early right ventricular failure and eventual cardiac failure, which lacks potential therapeutic targets. Our previous research demonstrated that T follicular helper (TFH) ce...

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Bibliographic Details
Main Authors: Cheng Li, Pingping Liu, Hao Zhu, Huan Yang, Jun Zha, Huiling Yao, Shaoze Zhang, Jin Huang, Guang Li, Gang Jiang, Yongliang Jiang, Aiguo Dai
Format: Article
Language:English
Published: BMC 2024-12-01
Series:Respiratory Research
Subjects:
T follicular helper cell
M2 macrophage
Pulmonary vascular remodeling
Hypoxia
Pulmonary hypertension
Online Access:https://doi.org/10.1186/s12931-024-03058-9
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