Choroid plexus enlargement contributes to motor severity via regional glymphatic dysfunction in Parkinson’s disease

Choroid plexus enlargement contributes to motor severity via regional glymphatic dysfunction in Parkinson’s disease

Abstract Choroid plexus (CP) enlargement and glymphatic dysfunction have been implicated in neurodegeneration, but their roles in Parkinson’s disease (PD) remain unclear. This retrospective cross-sectional study examined associations among CP volume, perivascular spaces (PVS), and motor symptom seve...

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Main Authors: Linyu Liu, Qiang Weng, Qing Cai, Xintong Yu, Weibin Huang, Shaohua Xie, Yan Shi, Huiting Li, Yuxuan Zhang, Jianping Hu, Mengcheng Li, Guannan Chen, Ning Wang, Xiang Lin, Ying Fu, Yu Lin
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:npj Parkinson's Disease
Online Access:https://doi.org/10.1038/s41531-025-00971-8
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