CHANGING IMAGE OF TKIS: ORIGINAL, BIOSIMILAR AND GENERIC OPTIONS
BCR-ABL is a 210 kDa protein that is required for the proliferation of CML-specific myeloid cells and has sustained kinase activity. Kinase activity provides uncontrolled signal transduction related to cell proliferation, apoptosis and adhesion. Although there are many tyrosine kinase enzymes, imati...
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| Main Author: | |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2024-12-01
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| Series: | Hematology, Transfusion and Cell Therapy |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2531137924029559 |
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