Cross-cultural translation, validation, and responsiveness of the Pittsburgh Fatigability Scale - Italian version (PFS-I) in a mixed-sample of older adults

Abstract Introduction Older adults experience fatigue which impacts health-related quality of life. The Pittsburgh Fatigability Scale (PFS) was specifically designed to assess perceived physical and mental fatigability in older adults. The aim of this study was to translate the PFS into Italian (PFS...

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Main Authors: Stefano Vercelli, Elisabetta Zampogna, Francesco Negrini, Chiara Pietraroia, Giuseppe D’Antona, Sonia Papa, Emiliano Soldini, Marco Barbero, Nancy W. Glynn, Matteo Beretta-Piccoli
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Language:English
Published: BMC 2024-12-01
Series:BMC Geriatrics
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Online Access:https://doi.org/10.1186/s12877-024-05603-z
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author Stefano Vercelli
Elisabetta Zampogna
Francesco Negrini
Chiara Pietraroia
Giuseppe D’Antona
Sonia Papa
Emiliano Soldini
Marco Barbero
Nancy W. Glynn
Matteo Beretta-Piccoli
author_facet Stefano Vercelli
Elisabetta Zampogna
Francesco Negrini
Chiara Pietraroia
Giuseppe D’Antona
Sonia Papa
Emiliano Soldini
Marco Barbero
Nancy W. Glynn
Matteo Beretta-Piccoli
author_sort Stefano Vercelli
collection DOAJ
description Abstract Introduction Older adults experience fatigue which impacts health-related quality of life. The Pittsburgh Fatigability Scale (PFS) was specifically designed to assess perceived physical and mental fatigability in older adults. The aim of this study was to translate the PFS into Italian (PFS-I) and to investigate its psychometric properties. Methods The PFS-I was translated in accordance with international standards. The following properties were evaluated: structural validity, internal consistency, hypotheses testing for construct validity, test-retest reliability using intraclass correlation coefficients (ICC), and minimal clinically important difference (MCID) for responsiveness. Results The study included 87 older adults with cardiovascular/respiratory diseases (CVRD), 46 with Parkinson disease (PD), and 67 healthy controls (HC). The PFS-I Physical and Mental subscales scores were significantly different in these populations, with HC reporting the lowest fatigability. Exploratory and confirmatory factor analysis showed a two-factor structure for both subscales, with good internal consistency (Cronbach’s alpha: 0.86 and 0.89, respectively). The PFS-I Physical subscale showed weak goodness-of-fit of the confirmatory factor analysis models, whereas the PFS-I Mental subscale was deemed acceptable. Construct validity of the PFS-I was excellent with 75% (18 out of 24) of hypotheses accepted. Test-retest reliability was analyzed in a subset of 23 patients with CVRD and showed excellent results for both the PFS-I Physical and Mental subscales (ICC = 0.93 and 0.92, respectively). MCID ranged between 6 and 7 points for the Physical and 7–9 points for the Mental subscale. Conclusions The PFS-I is a valid, reliable, and responsive instrument to assess perceived fatigability for healthy older adults as well as those with CRVD and PD.
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spelling doaj-art-ab2dd8af5fcd4b00bdcb1ec7cfb681e92025-08-20T01:57:12ZengBMCBMC Geriatrics1471-23182024-12-0124111510.1186/s12877-024-05603-zCross-cultural translation, validation, and responsiveness of the Pittsburgh Fatigability Scale - Italian version (PFS-I) in a mixed-sample of older adultsStefano Vercelli0Elisabetta Zampogna1Francesco Negrini2Chiara Pietraroia3Giuseppe D’Antona4Sonia Papa5Emiliano Soldini6Marco Barbero7Nancy W. Glynn8Matteo Beretta-Piccoli9Rehabilitation Research Laboratory 2rLab, Department of Business Economics, Health and Social Care, University of Applied Sciences and Arts of Southern SwitzerlandDivision of Pulmonary Rehabilitation, Istituti Clinici Scientifici Maugeri IRCCS, Scientific Institute of TradatePhysical and Rehabilitation Medicine Unit, Istituti Clinici Scientifici Maugeri IRCCS, Scientific Institute of TradateCriams-Sport Medicine Centre Voghera, University of PaviaCriams-Sport Medicine Centre Voghera, University of PaviaGeriatrics Competence Center, Clinica MoncuccoCompetence Centre for Healthcare Practices and Policies, Department of Business Economics, Health and Social Care, University of Applied Sciences and Arts of Southern SwitzerlandRehabilitation Research Laboratory 2rLab, Department of Business Economics, Health and Social Care, University of Applied Sciences and Arts of Southern SwitzerlandDepartment of Epidemiology, University of PittsburghRehabilitation Research Laboratory 2rLab, Department of Business Economics, Health and Social Care, University of Applied Sciences and Arts of Southern SwitzerlandAbstract Introduction Older adults experience fatigue which impacts health-related quality of life. The Pittsburgh Fatigability Scale (PFS) was specifically designed to assess perceived physical and mental fatigability in older adults. The aim of this study was to translate the PFS into Italian (PFS-I) and to investigate its psychometric properties. Methods The PFS-I was translated in accordance with international standards. The following properties were evaluated: structural validity, internal consistency, hypotheses testing for construct validity, test-retest reliability using intraclass correlation coefficients (ICC), and minimal clinically important difference (MCID) for responsiveness. Results The study included 87 older adults with cardiovascular/respiratory diseases (CVRD), 46 with Parkinson disease (PD), and 67 healthy controls (HC). The PFS-I Physical and Mental subscales scores were significantly different in these populations, with HC reporting the lowest fatigability. Exploratory and confirmatory factor analysis showed a two-factor structure for both subscales, with good internal consistency (Cronbach’s alpha: 0.86 and 0.89, respectively). The PFS-I Physical subscale showed weak goodness-of-fit of the confirmatory factor analysis models, whereas the PFS-I Mental subscale was deemed acceptable. Construct validity of the PFS-I was excellent with 75% (18 out of 24) of hypotheses accepted. Test-retest reliability was analyzed in a subset of 23 patients with CVRD and showed excellent results for both the PFS-I Physical and Mental subscales (ICC = 0.93 and 0.92, respectively). MCID ranged between 6 and 7 points for the Physical and 7–9 points for the Mental subscale. Conclusions The PFS-I is a valid, reliable, and responsive instrument to assess perceived fatigability for healthy older adults as well as those with CRVD and PD.https://doi.org/10.1186/s12877-024-05603-zFatigueOutcome measuresChronic respiratory diseaseCoronary heart diseaseParkinson diseaseRehabilitation
spellingShingle Stefano Vercelli
Elisabetta Zampogna
Francesco Negrini
Chiara Pietraroia
Giuseppe D’Antona
Sonia Papa
Emiliano Soldini
Marco Barbero
Nancy W. Glynn
Matteo Beretta-Piccoli
Cross-cultural translation, validation, and responsiveness of the Pittsburgh Fatigability Scale - Italian version (PFS-I) in a mixed-sample of older adults
BMC Geriatrics
Fatigue
Outcome measures
Chronic respiratory disease
Coronary heart disease
Parkinson disease
Rehabilitation
title Cross-cultural translation, validation, and responsiveness of the Pittsburgh Fatigability Scale - Italian version (PFS-I) in a mixed-sample of older adults
title_full Cross-cultural translation, validation, and responsiveness of the Pittsburgh Fatigability Scale - Italian version (PFS-I) in a mixed-sample of older adults
title_fullStr Cross-cultural translation, validation, and responsiveness of the Pittsburgh Fatigability Scale - Italian version (PFS-I) in a mixed-sample of older adults
title_full_unstemmed Cross-cultural translation, validation, and responsiveness of the Pittsburgh Fatigability Scale - Italian version (PFS-I) in a mixed-sample of older adults
title_short Cross-cultural translation, validation, and responsiveness of the Pittsburgh Fatigability Scale - Italian version (PFS-I) in a mixed-sample of older adults
title_sort cross cultural translation validation and responsiveness of the pittsburgh fatigability scale italian version pfs i in a mixed sample of older adults
topic Fatigue
Outcome measures
Chronic respiratory disease
Coronary heart disease
Parkinson disease
Rehabilitation
url https://doi.org/10.1186/s12877-024-05603-z
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