Towards Biocompatible Cellulose Nanofiber Sponges with Tailored Pore Geometries
Cellulose nanofiber (CNF) sponges or CNF aerogels are promising biocompatible materials with applications ranging from biomedicine to environmental remediation. The highly porous architecture of these sponges – which is crucial for their functionality – is significantly influenced by the freezing st...
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| Format: | Article |
| Language: | deu |
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Swiss Chemical Society
2025-04-01
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| Series: | CHIMIA |
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| Online Access: | https://www.chimia.ch/chimia/article/view/7940 |
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| author | Flavio Augusto von Philipsborn Christian Adlhart |
| author_facet | Flavio Augusto von Philipsborn Christian Adlhart |
| author_sort | Flavio Augusto von Philipsborn |
| collection | DOAJ |
| description | Cellulose nanofiber (CNF) sponges or CNF aerogels are promising biocompatible materials with applications ranging from biomedicine to environmental remediation. The highly porous architecture of these sponges – which is crucial for their functionality – is significantly influenced by the freezing step during fabrication. This review explores the critical role of freezing techniques in tailoring pore geometry and, consequently, the macroscopic properties of CNF sponges. We discuss conventional directional freezing methods and their limitations, highlighting the advantages of dynamic freezing for achieving isotropic pore structures. Furthermore, we examine various crosslinking strategies to enhance the stability and mechanical properties of CNF sponges. Finally, we present recent findings from our laboratory demonstrating the successful fabrication of biocompatible and crosslinked CNF sponges with tailored pore geometries using a dynamic freezing approach.
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| format | Article |
| id | doaj-art-ab2d64c638114c84a5c6d24864bbec9c |
| institution | OA Journals |
| issn | 0009-4293 2673-2424 |
| language | deu |
| publishDate | 2025-04-01 |
| publisher | Swiss Chemical Society |
| record_format | Article |
| series | CHIMIA |
| spelling | doaj-art-ab2d64c638114c84a5c6d24864bbec9c2025-08-20T01:47:32ZdeuSwiss Chemical SocietyCHIMIA0009-42932673-24242025-04-0179410.2533/chimia.2025.232Towards Biocompatible Cellulose Nanofiber Sponges with Tailored Pore GeometriesFlavio Augusto von Philipsborn0Christian Adlhart1Institute of Chemistry and Biotechnology, Zurich University of Applied Sciences ZHAW, CH-8820 Wädenswil, Switzerland; University of Zurich, Department of Chemistry, CH-8057 Zurich, Switzerland.Institute of Chemistry and Biotechnology, Zurich University of Applied Sciences ZHAW, CH-8820 Wädenswil, SwitzerlandCellulose nanofiber (CNF) sponges or CNF aerogels are promising biocompatible materials with applications ranging from biomedicine to environmental remediation. The highly porous architecture of these sponges – which is crucial for their functionality – is significantly influenced by the freezing step during fabrication. This review explores the critical role of freezing techniques in tailoring pore geometry and, consequently, the macroscopic properties of CNF sponges. We discuss conventional directional freezing methods and their limitations, highlighting the advantages of dynamic freezing for achieving isotropic pore structures. Furthermore, we examine various crosslinking strategies to enhance the stability and mechanical properties of CNF sponges. Finally, we present recent findings from our laboratory demonstrating the successful fabrication of biocompatible and crosslinked CNF sponges with tailored pore geometries using a dynamic freezing approach. https://www.chimia.ch/chimia/article/view/7940BiocompatibleCNF aerogelsCNF spongesCrosslinkingFreeze-dryingPore geometry |
| spellingShingle | Flavio Augusto von Philipsborn Christian Adlhart Towards Biocompatible Cellulose Nanofiber Sponges with Tailored Pore Geometries CHIMIA Biocompatible CNF aerogels CNF sponges Crosslinking Freeze-drying Pore geometry |
| title | Towards Biocompatible Cellulose Nanofiber Sponges with Tailored Pore Geometries |
| title_full | Towards Biocompatible Cellulose Nanofiber Sponges with Tailored Pore Geometries |
| title_fullStr | Towards Biocompatible Cellulose Nanofiber Sponges with Tailored Pore Geometries |
| title_full_unstemmed | Towards Biocompatible Cellulose Nanofiber Sponges with Tailored Pore Geometries |
| title_short | Towards Biocompatible Cellulose Nanofiber Sponges with Tailored Pore Geometries |
| title_sort | towards biocompatible cellulose nanofiber sponges with tailored pore geometries |
| topic | Biocompatible CNF aerogels CNF sponges Crosslinking Freeze-drying Pore geometry |
| url | https://www.chimia.ch/chimia/article/view/7940 |
| work_keys_str_mv | AT flavioaugustovonphilipsborn towardsbiocompatiblecellulosenanofiberspongeswithtailoredporegeometries AT christianadlhart towardsbiocompatiblecellulosenanofiberspongeswithtailoredporegeometries |