Biceps Tendon Rupture as an Early Manifestation of Hereditary Transthyretin Amyloidosis

Amyloidosis is a protein-folding disorder that leads to extracellular fibrillar deposition, often resulting in multiorgan dysfunction and tissue damage. Although several organs are subject to amyloid deposition, early identification and treatment of cardiac disease is crucial for efficacy of therapy...

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Main Authors: Christopher Hicks, Laura Cei, Qihua Fan, Sarah Paciulli, Jessica Frankenhoff, Lana Sargent, Cory Trankle, Keyur B. Shah
Format: Article
Language:English
Published: American College of Physicians 2024-03-01
Series:Annals of Internal Medicine: Clinical Cases
Online Access:https://www.acpjournals.org/doi/10.7326/aimcc.2023.1130
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author Christopher Hicks
Laura Cei
Qihua Fan
Sarah Paciulli
Jessica Frankenhoff
Lana Sargent
Cory Trankle
Keyur B. Shah
author_facet Christopher Hicks
Laura Cei
Qihua Fan
Sarah Paciulli
Jessica Frankenhoff
Lana Sargent
Cory Trankle
Keyur B. Shah
author_sort Christopher Hicks
collection DOAJ
description Amyloidosis is a protein-folding disorder that leads to extracellular fibrillar deposition, often resulting in multiorgan dysfunction and tissue damage. Although several organs are subject to amyloid deposition, early identification and treatment of cardiac disease is crucial for efficacy of therapy. Here, we describe the cases of 2 men who reported biceps tendon ruptures several years before their diagnosis of cardiac amyloidosis.
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issn 2767-7664
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publishDate 2024-03-01
publisher American College of Physicians
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series Annals of Internal Medicine: Clinical Cases
spelling doaj-art-ab29cc77e6684f3aa375c92dc93feace2025-08-20T02:12:58ZengAmerican College of PhysiciansAnnals of Internal Medicine: Clinical Cases2767-76642024-03-013310.7326/aimcc.2023.1130Biceps Tendon Rupture as an Early Manifestation of Hereditary Transthyretin AmyloidosisChristopher Hicks0Laura Cei1Qihua Fan2Sarah Paciulli3Jessica Frankenhoff4Lana Sargent5Cory Trankle6Keyur B. Shah71The Pauley Heart Center, Virginia Commonwealth University, Richmond, Virginia2School of Nursing, Virginia Commonwealth University, Richmond, Virginia3Department of Neurology, Virginia Commonwealth University, Richmond, Virginia1The Pauley Heart Center, Virginia Commonwealth University, Richmond, Virginia4Department of Orthopedic Surgery, Virginia Commonwealth University, Richmond, Virginia1The Pauley Heart Center, Virginia Commonwealth University, Richmond, Virginia1The Pauley Heart Center, Virginia Commonwealth University, Richmond, Virginia1The Pauley Heart Center, Virginia Commonwealth University, Richmond, VirginiaAmyloidosis is a protein-folding disorder that leads to extracellular fibrillar deposition, often resulting in multiorgan dysfunction and tissue damage. Although several organs are subject to amyloid deposition, early identification and treatment of cardiac disease is crucial for efficacy of therapy. Here, we describe the cases of 2 men who reported biceps tendon ruptures several years before their diagnosis of cardiac amyloidosis.https://www.acpjournals.org/doi/10.7326/aimcc.2023.1130
spellingShingle Christopher Hicks
Laura Cei
Qihua Fan
Sarah Paciulli
Jessica Frankenhoff
Lana Sargent
Cory Trankle
Keyur B. Shah
Biceps Tendon Rupture as an Early Manifestation of Hereditary Transthyretin Amyloidosis
Annals of Internal Medicine: Clinical Cases
title Biceps Tendon Rupture as an Early Manifestation of Hereditary Transthyretin Amyloidosis
title_full Biceps Tendon Rupture as an Early Manifestation of Hereditary Transthyretin Amyloidosis
title_fullStr Biceps Tendon Rupture as an Early Manifestation of Hereditary Transthyretin Amyloidosis
title_full_unstemmed Biceps Tendon Rupture as an Early Manifestation of Hereditary Transthyretin Amyloidosis
title_short Biceps Tendon Rupture as an Early Manifestation of Hereditary Transthyretin Amyloidosis
title_sort biceps tendon rupture as an early manifestation of hereditary transthyretin amyloidosis
url https://www.acpjournals.org/doi/10.7326/aimcc.2023.1130
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