Statins in prevention of postoperative cognitive dysfunction in patients after cardiac surgery
On-pump CABG is commonly accompanied by the development of postoperative cognitive dysfunction considerably affecting the prognosis in this group of patients. However, there are no accepted guidelines on diagnostics and prevention of postoperative cognitive dysfunction. Here we review the incidence,...
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| Format: | Article |
| Language: | Russian |
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Kemerovo State Medical University
2019-06-01
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| Series: | Фундаментальная и клиническая медицина |
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| Online Access: | https://fcm.kemsmu.ru/jour/article/view/148 |
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| _version_ | 1850064918151168000 |
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| author | O. V. Maleva O. A. Trubnikova O. L. Barbarash |
| author_facet | O. V. Maleva O. A. Trubnikova O. L. Barbarash |
| author_sort | O. V. Maleva |
| collection | DOAJ |
| description | On-pump CABG is commonly accompanied by the development of postoperative cognitive dysfunction considerably affecting the prognosis in this group of patients. However, there are no accepted guidelines on diagnostics and prevention of postoperative cognitive dysfunction. Here we review the incidence, mechanisms, and outcomes of postoperative cognitive dysfunction after coronary artery bypass graft surgery and highlight the benefits of statins for its prevention. We further provide evidence from national and international studies assessing the role of statins in the prevention of postoperative cognitive dysfunction. |
| format | Article |
| id | doaj-art-ab1d16331ec94ae191a15573e710ad62 |
| institution | DOAJ |
| issn | 2500-0764 2542-0941 |
| language | Russian |
| publishDate | 2019-06-01 |
| publisher | Kemerovo State Medical University |
| record_format | Article |
| series | Фундаментальная и клиническая медицина |
| spelling | doaj-art-ab1d16331ec94ae191a15573e710ad622025-08-20T02:49:09ZrusKemerovo State Medical UniversityФундаментальная и клиническая медицина2500-07642542-09412019-06-01429510610.23946/2500-0764-2019-4-2-95-106147Statins in prevention of postoperative cognitive dysfunction in patients after cardiac surgeryO. V. Maleva0O. A. Trubnikova1O. L. Barbarash2Research Institute for Complex Issues ofCardiovascular DiseasesResearch Institute for Complex Issues ofCardiovascular DiseasesResearch Institute for Complex Issues ofCardiovascular Diseases; Kemerovo State Medical UniversityOn-pump CABG is commonly accompanied by the development of postoperative cognitive dysfunction considerably affecting the prognosis in this group of patients. However, there are no accepted guidelines on diagnostics and prevention of postoperative cognitive dysfunction. Here we review the incidence, mechanisms, and outcomes of postoperative cognitive dysfunction after coronary artery bypass graft surgery and highlight the benefits of statins for its prevention. We further provide evidence from national and international studies assessing the role of statins in the prevention of postoperative cognitive dysfunction.https://fcm.kemsmu.ru/jour/article/view/148postoperative cognitive dysfunctioncoronary artery bypass graftingstatins |
| spellingShingle | O. V. Maleva O. A. Trubnikova O. L. Barbarash Statins in prevention of postoperative cognitive dysfunction in patients after cardiac surgery Фундаментальная и клиническая медицина postoperative cognitive dysfunction coronary artery bypass grafting statins |
| title | Statins in prevention of postoperative cognitive dysfunction in patients after cardiac surgery |
| title_full | Statins in prevention of postoperative cognitive dysfunction in patients after cardiac surgery |
| title_fullStr | Statins in prevention of postoperative cognitive dysfunction in patients after cardiac surgery |
| title_full_unstemmed | Statins in prevention of postoperative cognitive dysfunction in patients after cardiac surgery |
| title_short | Statins in prevention of postoperative cognitive dysfunction in patients after cardiac surgery |
| title_sort | statins in prevention of postoperative cognitive dysfunction in patients after cardiac surgery |
| topic | postoperative cognitive dysfunction coronary artery bypass grafting statins |
| url | https://fcm.kemsmu.ru/jour/article/view/148 |
| work_keys_str_mv | AT ovmaleva statinsinpreventionofpostoperativecognitivedysfunctioninpatientsaftercardiacsurgery AT oatrubnikova statinsinpreventionofpostoperativecognitivedysfunctioninpatientsaftercardiacsurgery AT olbarbarash statinsinpreventionofpostoperativecognitivedysfunctioninpatientsaftercardiacsurgery |