Comparison and Analysis of the Drug-Resistance Mechanism of Osimertinib- and Almonertinib-Resistant Cell Lines
Conclusions: These findings indicated that almonertinib and osimertinib exhibited distinct resistance mechanisms in vitro, underscoring the need for tailored treatment approaches.
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| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2025-01-01
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| Series: | Analytical Cellular Pathology |
| Online Access: | http://dx.doi.org/10.1155/ancp/5578693 |
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| _version_ | 1849729622608969728 |
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| author | Chuangjie Zheng Yingfang Ren Ke Wang Xinrong Chen Jiahao Tao Cuifen Zhang Zeyu Liu Lingling Sun Linzhu Zhai |
| author_facet | Chuangjie Zheng Yingfang Ren Ke Wang Xinrong Chen Jiahao Tao Cuifen Zhang Zeyu Liu Lingling Sun Linzhu Zhai |
| author_sort | Chuangjie Zheng |
| collection | DOAJ |
| description | Conclusions: These findings indicated that almonertinib and osimertinib exhibited distinct resistance mechanisms in vitro, underscoring the need for tailored treatment approaches. |
| format | Article |
| id | doaj-art-ab16dab3bf1f41b9963b9b4f65992588 |
| institution | DOAJ |
| issn | 2210-7185 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Analytical Cellular Pathology |
| spelling | doaj-art-ab16dab3bf1f41b9963b9b4f659925882025-08-20T03:09:09ZengWileyAnalytical Cellular Pathology2210-71852025-01-01202510.1155/ancp/5578693Comparison and Analysis of the Drug-Resistance Mechanism of Osimertinib- and Almonertinib-Resistant Cell LinesChuangjie Zheng0Yingfang Ren1Ke Wang2Xinrong Chen3Jiahao Tao4Cuifen Zhang5Zeyu Liu6Lingling Sun7Linzhu Zhai8Cancer CenterCancer CenterCancer CenterCancer CenterCancer CenterCancer CenterCancer CenterCancer CenterCancer CenterConclusions: These findings indicated that almonertinib and osimertinib exhibited distinct resistance mechanisms in vitro, underscoring the need for tailored treatment approaches.http://dx.doi.org/10.1155/ancp/5578693 |
| spellingShingle | Chuangjie Zheng Yingfang Ren Ke Wang Xinrong Chen Jiahao Tao Cuifen Zhang Zeyu Liu Lingling Sun Linzhu Zhai Comparison and Analysis of the Drug-Resistance Mechanism of Osimertinib- and Almonertinib-Resistant Cell Lines Analytical Cellular Pathology |
| title | Comparison and Analysis of the Drug-Resistance Mechanism of Osimertinib- and Almonertinib-Resistant Cell Lines |
| title_full | Comparison and Analysis of the Drug-Resistance Mechanism of Osimertinib- and Almonertinib-Resistant Cell Lines |
| title_fullStr | Comparison and Analysis of the Drug-Resistance Mechanism of Osimertinib- and Almonertinib-Resistant Cell Lines |
| title_full_unstemmed | Comparison and Analysis of the Drug-Resistance Mechanism of Osimertinib- and Almonertinib-Resistant Cell Lines |
| title_short | Comparison and Analysis of the Drug-Resistance Mechanism of Osimertinib- and Almonertinib-Resistant Cell Lines |
| title_sort | comparison and analysis of the drug resistance mechanism of osimertinib and almonertinib resistant cell lines |
| url | http://dx.doi.org/10.1155/ancp/5578693 |
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