Considerable decline in prostate cancer mortality in Nordic countries after 2000
Background and purpose: In the late 1990s, the Nordic countries, with Norway at the top, were among the countries with the highest prostate cancer mortality in the world. We present updated mortality rates from the Nordic countries and discuss possible interpretations of changes in trends. Material...
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| Language: | English |
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Medical Journals Sweden
2025-01-01
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| Series: | Acta Oncologica |
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| Online Access: | https://medicaljournalssweden.se/actaoncologica/article/view/41334 |
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| _version_ | 1832583804414328832 |
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| author | Rune Kvåle Giske Ursin Christian Ekanger Bjørn Møller |
| author_facet | Rune Kvåle Giske Ursin Christian Ekanger Bjørn Møller |
| author_sort | Rune Kvåle |
| collection | DOAJ |
| description | Background and purpose: In the late 1990s, the Nordic countries, with Norway at the top, were among the countries with the highest prostate cancer mortality in the world. We present updated mortality rates from the Nordic countries and discuss possible interpretations of changes in trends.
Material and methods: Age-standardized rates for prostate-specific mortality in 1985–2022, estimated lifetime risk of death (0–84 years) and annual changes in mortality were obtained from the NORDCAN database. Joinpoint regression was used to evaluate trend changes for the period 1985–2022. For comparison, rates from other European countries from 2022 were retrieved from the GLOBOCAN database.
Results: Between 1995–99 and 2018–22, mortality in men aged 40–84 years decreased from 38% in Denmark to 59% in Norway. By 2022 Norway had the second lowest mortality among the Nordic countries overall, and the lowest under 85 years. The life-time risk of dying from prostate cancer declined from 5.6–7.1% in 1995–99 to 3.1–4.2% in the last 5-year period. During the last years mortality has decreased most rapidly in Sweden (4.5% annually from 2016) and Norway (4.3% annually from 2014). The Nordic countries are no longer among the countries with the highest mortality in Europe.
Interpretation: Mortality from prostate cancer has decreased significantly in the Nordic countries over the last decades. Possible explanatory factors are likely to include improvements in prostate cancer management strategies and treatment.
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| format | Article |
| id | doaj-art-ab16b6cf3963429289010beabd3f4a7a |
| institution | Kabale University |
| issn | 1651-226X |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Medical Journals Sweden |
| record_format | Article |
| series | Acta Oncologica |
| spelling | doaj-art-ab16b6cf3963429289010beabd3f4a7a2025-01-28T06:40:52ZengMedical Journals SwedenActa Oncologica1651-226X2025-01-016410.2340/1651-226X.2025.41334Considerable decline in prostate cancer mortality in Nordic countries after 2000Rune Kvåle0https://orcid.org/0000-0002-4106-230XGiske Ursin1https://orcid.org/0000-0002-0835-9507Christian Ekanger2https://orcid.org/0000-0002-6526-7174Bjørn Møller3https://orcid.org/0000-0002-4770-1889Cancer Registry of Norway, Norwegian Institute of Public Health, Oslo, Norway; Department of Oncology and Medical Physics, Haukeland University Hospital, Bergen, NorwayCancer Registry of Norway, Norwegian Institute of Public Health, Oslo, Norway; Department of Nutrition, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway; Department of Preventive Medicine, University of Southern California, Los Angeles, CA, USADepartment of Oncology and Medical Physics, Haukeland University Hospital, Bergen, NorwayCancer Registry of Norway, Norwegian Institute of Public Health, Oslo, NorwayBackground and purpose: In the late 1990s, the Nordic countries, with Norway at the top, were among the countries with the highest prostate cancer mortality in the world. We present updated mortality rates from the Nordic countries and discuss possible interpretations of changes in trends. Material and methods: Age-standardized rates for prostate-specific mortality in 1985–2022, estimated lifetime risk of death (0–84 years) and annual changes in mortality were obtained from the NORDCAN database. Joinpoint regression was used to evaluate trend changes for the period 1985–2022. For comparison, rates from other European countries from 2022 were retrieved from the GLOBOCAN database. Results: Between 1995–99 and 2018–22, mortality in men aged 40–84 years decreased from 38% in Denmark to 59% in Norway. By 2022 Norway had the second lowest mortality among the Nordic countries overall, and the lowest under 85 years. The life-time risk of dying from prostate cancer declined from 5.6–7.1% in 1995–99 to 3.1–4.2% in the last 5-year period. During the last years mortality has decreased most rapidly in Sweden (4.5% annually from 2016) and Norway (4.3% annually from 2014). The Nordic countries are no longer among the countries with the highest mortality in Europe. Interpretation: Mortality from prostate cancer has decreased significantly in the Nordic countries over the last decades. Possible explanatory factors are likely to include improvements in prostate cancer management strategies and treatment. https://medicaljournalssweden.se/actaoncologica/article/view/41334Prostate cancerNordic countriesMortality trends |
| spellingShingle | Rune Kvåle Giske Ursin Christian Ekanger Bjørn Møller Considerable decline in prostate cancer mortality in Nordic countries after 2000 Acta Oncologica Prostate cancer Nordic countries Mortality trends |
| title | Considerable decline in prostate cancer mortality in Nordic countries after 2000 |
| title_full | Considerable decline in prostate cancer mortality in Nordic countries after 2000 |
| title_fullStr | Considerable decline in prostate cancer mortality in Nordic countries after 2000 |
| title_full_unstemmed | Considerable decline in prostate cancer mortality in Nordic countries after 2000 |
| title_short | Considerable decline in prostate cancer mortality in Nordic countries after 2000 |
| title_sort | considerable decline in prostate cancer mortality in nordic countries after 2000 |
| topic | Prostate cancer Nordic countries Mortality trends |
| url | https://medicaljournalssweden.se/actaoncologica/article/view/41334 |
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