Prognostic significance of D-dimer, neuron-specific enolase, and lactate dehydrogenase changes in patients with severe traumatic brain injury: a logistic regression analysis
The retrospective study was conducted at Baoding No.1 Central Hospital, China, and comprised data from July 2021 to January 2023, and aimed at exploring the relationship of neuron-specific enolase, D-dimer and lactate dehydrogenase with prognosis in patients with serous traumatic brain injury. Data...
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Pakistan Medical Association
2024-12-01
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| Series: | Journal of the Pakistan Medical Association |
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| Online Access: | https://jpma.org.pk/index.php/public_html/article/view/11088 |
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| author | Jing Xie Lu Zhang Ning Gan |
| author_facet | Jing Xie Lu Zhang Ning Gan |
| author_sort | Jing Xie |
| collection | DOAJ |
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The retrospective study was conducted at Baoding No.1 Central Hospital, China, and comprised data from July 2021 to January 2023, and aimed at exploring the relationship of neuron-specific enolase, D-dimer and lactate dehydrogenase with prognosis in patients with serous traumatic brain injury. Data of 100 patients was categorised into favourable prognosis group A having 50(50%) patients and unfavourable prognosis group B having 50(50%) patients, and was compared with as many healthy controls in group C. Increase in neuron-specific enolase, D-dimer and lactate dehydrogenase concentrations was significantly elevated in groups A and B compared to group C (p<0.05), and in group B compared to group A (p<0.05).
Key Words: Severe traumatic brain injury, Neuron-specific enolase, D-dimer, Lactate dehydrogenase, Risk factors.
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| format | Article |
| id | doaj-art-ab155cc3ba574355acfb350becfa5bff |
| institution | DOAJ |
| issn | 0030-9982 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Pakistan Medical Association |
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| series | Journal of the Pakistan Medical Association |
| spelling | doaj-art-ab155cc3ba574355acfb350becfa5bff2025-08-20T02:41:30ZengPakistan Medical AssociationJournal of the Pakistan Medical Association0030-99822024-12-0175110.47391/JPMA.11088Prognostic significance of D-dimer, neuron-specific enolase, and lactate dehydrogenase changes in patients with severe traumatic brain injury: a logistic regression analysisJing Xie0Lu Zhang1Ning Gan2Department of Neurosurgery, Baoding No.1 Central Hospital, Baoding, ChinaDepartment of Neurosurgery, Baoding No.1 Central Hospital, Baoding, ChinaDepartment of Neurosurgery, Baoding No.1 Central Hospital, Baoding, China The retrospective study was conducted at Baoding No.1 Central Hospital, China, and comprised data from July 2021 to January 2023, and aimed at exploring the relationship of neuron-specific enolase, D-dimer and lactate dehydrogenase with prognosis in patients with serous traumatic brain injury. Data of 100 patients was categorised into favourable prognosis group A having 50(50%) patients and unfavourable prognosis group B having 50(50%) patients, and was compared with as many healthy controls in group C. Increase in neuron-specific enolase, D-dimer and lactate dehydrogenase concentrations was significantly elevated in groups A and B compared to group C (p<0.05), and in group B compared to group A (p<0.05). Key Words: Severe traumatic brain injury, Neuron-specific enolase, D-dimer, Lactate dehydrogenase, Risk factors. https://jpma.org.pk/index.php/public_html/article/view/11088severe traumatic brain injuryNeuron-specific enolaseD-dimerLactate dehydrogenaseRisk factors |
| spellingShingle | Jing Xie Lu Zhang Ning Gan Prognostic significance of D-dimer, neuron-specific enolase, and lactate dehydrogenase changes in patients with severe traumatic brain injury: a logistic regression analysis Journal of the Pakistan Medical Association severe traumatic brain injury Neuron-specific enolase D-dimer Lactate dehydrogenase Risk factors |
| title | Prognostic significance of D-dimer, neuron-specific enolase, and lactate dehydrogenase changes in patients with severe traumatic brain injury: a logistic regression analysis |
| title_full | Prognostic significance of D-dimer, neuron-specific enolase, and lactate dehydrogenase changes in patients with severe traumatic brain injury: a logistic regression analysis |
| title_fullStr | Prognostic significance of D-dimer, neuron-specific enolase, and lactate dehydrogenase changes in patients with severe traumatic brain injury: a logistic regression analysis |
| title_full_unstemmed | Prognostic significance of D-dimer, neuron-specific enolase, and lactate dehydrogenase changes in patients with severe traumatic brain injury: a logistic regression analysis |
| title_short | Prognostic significance of D-dimer, neuron-specific enolase, and lactate dehydrogenase changes in patients with severe traumatic brain injury: a logistic regression analysis |
| title_sort | prognostic significance of d dimer neuron specific enolase and lactate dehydrogenase changes in patients with severe traumatic brain injury a logistic regression analysis |
| topic | severe traumatic brain injury Neuron-specific enolase D-dimer Lactate dehydrogenase Risk factors |
| url | https://jpma.org.pk/index.php/public_html/article/view/11088 |
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