Amino acid insertion in the Meq protein of Marek’s disease virus, an avian oncogenic herpesvirus, accelerates tumorigenesis

Amino acid insertion in the Meq protein of Marek’s disease virus, an avian oncogenic herpesvirus, accelerates tumorigenesis

ABSTRACT Marek’s disease virus (MDV) causes lymphomas (Marek’s disease) in chickens. Despite vaccination, MDV field strains exhibit increased virulence, and sporadic outbreaks are still reported. An insertion/deletion in Meq has been identified in several MDV strains, and our previous study using re...

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Main Authors: Jumpei Sato, Shiro Murata, Yoshinosuke Motai, Shwe Yee Win, Hikari Seo, Shunsuke Yamagami, Naoya Maekawa, Tomohiro Okagawa, Satoru Konnai, Kazuhiko Ohashi
Format: Article
Language:English
Published: American Society for Microbiology 2025-08-01
Series:Microbiology Spectrum
Subjects:
Marek's disease virus
Marek's disease
Meq
L-Meq
insertion
tumorigenesis
Online Access:https://journals.asm.org/doi/10.1128/spectrum.03368-24
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