Exogenous Phosphocreatine Application in Elderly and Senile Patients Operated for Colorectal Cancer
Objective: to evaluate the efficacy of exogenous phosphocreatine (EPCr) application in elderly and senile patients operated for colorectal cancer.Material and methods. 80 patients with routine perioperative management (Group 1) and 56 patients in whom routine perioperative management was supplemente...
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| Language: | English |
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Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, Russia
2017-09-01
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| Series: | Общая реаниматология |
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| Online Access: | https://www.reanimatology.com/rmt/article/view/1602 |
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| author | V. N. Derbugov A. L. Potapov V. I. Potievskaya Ya. M. Khmelevski |
| author_facet | V. N. Derbugov A. L. Potapov V. I. Potievskaya Ya. M. Khmelevski |
| author_sort | V. N. Derbugov |
| collection | DOAJ |
| description | Objective: to evaluate the efficacy of exogenous phosphocreatine (EPCr) application in elderly and senile patients operated for colorectal cancer.Material and methods. 80 patients with routine perioperative management (Group 1) and 56 patients in whom routine perioperative management was supplemented with EPCr administration (Group 2). Postoperative morbidity and duration of hospitalization after surgery have been assessed in both groups.Results. Postoperative morbidity was lower in Group 2: 7.2% vs. 35% (P=0.001; OR=0.18; 95% CI: 0.07—0.49), mainly due to decreasing the incidence of acute coronary syndrome and anastomotic leakage. The duration of hospi% talization after surgery was lower in Group 2 as well.Conclusions. Application of EPCr might be an effective measure to decrease the postoperative morbidity in elderly and senile patients with colorectal cancer. |
| format | Article |
| id | doaj-art-ab1297abfd8b4eee8a1142940b11f80c |
| institution | Kabale University |
| issn | 1813-9779 2411-7110 |
| language | English |
| publishDate | 2017-09-01 |
| publisher | Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, Russia |
| record_format | Article |
| series | Общая реаниматология |
| spelling | doaj-art-ab1297abfd8b4eee8a1142940b11f80c2025-08-20T03:59:40ZengFederal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, RussiaОбщая реаниматология1813-97792411-71102017-09-01134384510.15360/1813-9779-2017-4-38-451565Exogenous Phosphocreatine Application in Elderly and Senile Patients Operated for Colorectal CancerV. N. Derbugov0A. L. Potapov1V. I. Potievskaya2Ya. M. Khmelevski3A. F. Tsyba Medical Radiological Research Center, National Medical Radiological Research Center, Ministry of Health of RussiaA. F. Tsyba Medical Radiological Research Center, National Medical Radiological Research Center, Ministry of Health of RussiaA. F. Tsyba Medical Radiological Research Center, National Medical Radiological Research Center, Ministry of Health of RussiaA. F. Tsyba Medical Radiological Research Center, National Medical Radiological Research Center, Ministry of Health of RussiaObjective: to evaluate the efficacy of exogenous phosphocreatine (EPCr) application in elderly and senile patients operated for colorectal cancer.Material and methods. 80 patients with routine perioperative management (Group 1) and 56 patients in whom routine perioperative management was supplemented with EPCr administration (Group 2). Postoperative morbidity and duration of hospitalization after surgery have been assessed in both groups.Results. Postoperative morbidity was lower in Group 2: 7.2% vs. 35% (P=0.001; OR=0.18; 95% CI: 0.07—0.49), mainly due to decreasing the incidence of acute coronary syndrome and anastomotic leakage. The duration of hospi% talization after surgery was lower in Group 2 as well.Conclusions. Application of EPCr might be an effective measure to decrease the postoperative morbidity in elderly and senile patients with colorectal cancer.https://www.reanimatology.com/rmt/article/view/1602colorectal cancersurgeryexogenous phosphocreatine |
| spellingShingle | V. N. Derbugov A. L. Potapov V. I. Potievskaya Ya. M. Khmelevski Exogenous Phosphocreatine Application in Elderly and Senile Patients Operated for Colorectal Cancer Общая реаниматология colorectal cancer surgery exogenous phosphocreatine |
| title | Exogenous Phosphocreatine Application in Elderly and Senile Patients Operated for Colorectal Cancer |
| title_full | Exogenous Phosphocreatine Application in Elderly and Senile Patients Operated for Colorectal Cancer |
| title_fullStr | Exogenous Phosphocreatine Application in Elderly and Senile Patients Operated for Colorectal Cancer |
| title_full_unstemmed | Exogenous Phosphocreatine Application in Elderly and Senile Patients Operated for Colorectal Cancer |
| title_short | Exogenous Phosphocreatine Application in Elderly and Senile Patients Operated for Colorectal Cancer |
| title_sort | exogenous phosphocreatine application in elderly and senile patients operated for colorectal cancer |
| topic | colorectal cancer surgery exogenous phosphocreatine |
| url | https://www.reanimatology.com/rmt/article/view/1602 |
| work_keys_str_mv | AT vnderbugov exogenousphosphocreatineapplicationinelderlyandsenilepatientsoperatedforcolorectalcancer AT alpotapov exogenousphosphocreatineapplicationinelderlyandsenilepatientsoperatedforcolorectalcancer AT vipotievskaya exogenousphosphocreatineapplicationinelderlyandsenilepatientsoperatedforcolorectalcancer AT yamkhmelevski exogenousphosphocreatineapplicationinelderlyandsenilepatientsoperatedforcolorectalcancer |