Cell cycle dependence of ERK activation dynamics is regulated by PI3K and PAK1 signaling
Abstract Growth factor-induced RTK/RAS/MAPK signaling is crucial for cell cycle progression, including G1 to S and G2 to M phase transitions. However, the regulatory mechanism of MAPK (ERK) in the S–G2M phase remains unclear. In this study, we analyzed the nuclear translocation dynamics of fluoresce...
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| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-07-01
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| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-025-13686-w |
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