Association Between Serum Uric Acid Level and Psoriasis: A Case Control Study
Introduction: Psoriasis is a common, chronic, inflammatory and proliferative condition of the skin, associated with various disorders including metabolic syndrome. High serum uric acid levels are also associated with metabolic syndrome. Hyperuricemia is associated with psoriasis and psoriatic arthr...
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Society of Dermatologists, Venereologists and Leprologists of Nepal (SODVELON)
2021-04-01
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| Series: | Nepal Journal of Dermatology, Venereology & Leprology |
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| Online Access: | https://www.nepjol.info/index.php/NJDVL/article/view/35958 |
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| author | Aruna Sayami Aatmaram Gupta Narayan Gautam |
| author_facet | Aruna Sayami Aatmaram Gupta Narayan Gautam |
| author_sort | Aruna Sayami |
| collection | DOAJ |
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Introduction: Psoriasis is a common, chronic, inflammatory and proliferative condition of the skin, associated with various disorders including metabolic syndrome. High serum uric acid levels are also associated with metabolic syndrome. Hyperuricemia is associated with psoriasis and psoriatic arthritis.
Objectives: To find out the association of serum uric acid with psoriasis.
Materials and Method: It was a case-control study including 104 patients, among them 52 were psoriatic patients (case) and 52 had disease other than psoriasis (control) after matching for age and sex. The study was conducted at Department of Dermatology, Universal College of Medical Science, from January- December 2017. Clinical examination and proforma documentation including patient details, laboratory values of serum uric acid level, Psoriasis Area and Severity Index score were studied.
Results: Mean SUA in psoriasis patients was 4.70±1.37 mg/dl in female, 5.57±1.18 mg/dl in male whereas 4.85±0.74 mg/dl in female and 4.34 ± 0.98 mg/dl in male respectively in control group (p=0.002). Six (18.88%) male and three (15.78%) female patients with psoriasis had higher serum uric acid value whereas only four (3.84%) patient had higherserum uric acid value in control group (p=0.012). There was association between serum uric acid and psoriasis.
Conclusion: Our study concludes that serum uric acid level is increased in psoriasis patients when compared with controls. Monitoring of psoriatic patients for high serum uric acid levels during treatment and follow up should be done to prevent the its deleterious effect on psoriasis.
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| format | Article |
| id | doaj-art-ab03d789dee7450b9cdb2f16ae530cb2 |
| institution | Kabale University |
| issn | 2091-0231 2091-167X |
| language | English |
| publishDate | 2021-04-01 |
| publisher | Society of Dermatologists, Venereologists and Leprologists of Nepal (SODVELON) |
| record_format | Article |
| series | Nepal Journal of Dermatology, Venereology & Leprology |
| spelling | doaj-art-ab03d789dee7450b9cdb2f16ae530cb22025-08-23T10:04:11ZengSociety of Dermatologists, Venereologists and Leprologists of Nepal (SODVELON)Nepal Journal of Dermatology, Venereology & Leprology2091-02312091-167X2021-04-0119110.3126/njdvl.v19i1.35958Association Between Serum Uric Acid Level and Psoriasis: A Case Control StudyAruna Sayami0Aatmaram Gupta1Narayan Gautam2Department of Dermatology, Venerology and Leprology, Institute of Medicine, Tribhuwan UniversityDepartment of Dermatology, Venerology and Leprology Universal College of Medical Sciences, Bhairahawa, NepalDepartment of Microbiology, Universal College of Medical Sciences, Bhairahawa Introduction: Psoriasis is a common, chronic, inflammatory and proliferative condition of the skin, associated with various disorders including metabolic syndrome. High serum uric acid levels are also associated with metabolic syndrome. Hyperuricemia is associated with psoriasis and psoriatic arthritis. Objectives: To find out the association of serum uric acid with psoriasis. Materials and Method: It was a case-control study including 104 patients, among them 52 were psoriatic patients (case) and 52 had disease other than psoriasis (control) after matching for age and sex. The study was conducted at Department of Dermatology, Universal College of Medical Science, from January- December 2017. Clinical examination and proforma documentation including patient details, laboratory values of serum uric acid level, Psoriasis Area and Severity Index score were studied. Results: Mean SUA in psoriasis patients was 4.70±1.37 mg/dl in female, 5.57±1.18 mg/dl in male whereas 4.85±0.74 mg/dl in female and 4.34 ± 0.98 mg/dl in male respectively in control group (p=0.002). Six (18.88%) male and three (15.78%) female patients with psoriasis had higher serum uric acid value whereas only four (3.84%) patient had higherserum uric acid value in control group (p=0.012). There was association between serum uric acid and psoriasis. Conclusion: Our study concludes that serum uric acid level is increased in psoriasis patients when compared with controls. Monitoring of psoriatic patients for high serum uric acid levels during treatment and follow up should be done to prevent the its deleterious effect on psoriasis. https://www.nepjol.info/index.php/NJDVL/article/view/35958hyperuricemiapsoriasispsoriatic arthritisserum uric acid. |
| spellingShingle | Aruna Sayami Aatmaram Gupta Narayan Gautam Association Between Serum Uric Acid Level and Psoriasis: A Case Control Study Nepal Journal of Dermatology, Venereology & Leprology hyperuricemia psoriasis psoriatic arthritis serum uric acid. |
| title | Association Between Serum Uric Acid Level and Psoriasis: A Case Control Study |
| title_full | Association Between Serum Uric Acid Level and Psoriasis: A Case Control Study |
| title_fullStr | Association Between Serum Uric Acid Level and Psoriasis: A Case Control Study |
| title_full_unstemmed | Association Between Serum Uric Acid Level and Psoriasis: A Case Control Study |
| title_short | Association Between Serum Uric Acid Level and Psoriasis: A Case Control Study |
| title_sort | association between serum uric acid level and psoriasis a case control study |
| topic | hyperuricemia psoriasis psoriatic arthritis serum uric acid. |
| url | https://www.nepjol.info/index.php/NJDVL/article/view/35958 |
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