A high-quality Chromosome-level reference genome assembly of white-lipped deer (Przewalskium albirostris)

Abstract White-lipped deer (Przewalskium albirostris) is the sole species in the genus Przewalskium of the Cervidae family. And it is exclusively found in the Qinghai-Tibet Plateau, where it has evolved as a specialized deer on account of the extreme climates and geographical conditions. However, li...

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Main Authors: Yuangang Yang, Bin Li, Wei Luo, Bo Xu, Peng Luo, Tongzuo Zhang, Zhangqiang You
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Scientific Data
Online Access:https://doi.org/10.1038/s41597-025-04796-1
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author Yuangang Yang
Bin Li
Wei Luo
Bo Xu
Peng Luo
Tongzuo Zhang
Zhangqiang You
author_facet Yuangang Yang
Bin Li
Wei Luo
Bo Xu
Peng Luo
Tongzuo Zhang
Zhangqiang You
author_sort Yuangang Yang
collection DOAJ
description Abstract White-lipped deer (Przewalskium albirostris) is the sole species in the genus Przewalskium of the Cervidae family. And it is exclusively found in the Qinghai-Tibet Plateau, where it has evolved as a specialized deer on account of the extreme climates and geographical conditions. However, limited research on the genome of this species exists. Here, PacBio and Hi-C sequencing data were constructed to a high-quality Chromosome-level reference genome for the white-lipped deer. The assembly, totaling 2.99 GB, is composed of 34 chromosomes (32 autosomes and X, Y chromosomes), with a scaffold N50 length of 76.18 Mb. Furthermore, it achieved scores of 98.4% and 63.8 in Universal Single-Copy Ortholog (BUSCO) and quality value (QV), respectively. Subsequently, employing the egapx software for genome structural annotation, we identified a total of 21909 protein coding genes, annotating 21859 of them. The high-quality and completeness of our genome sequence and annotation was affirmed by these results. The assembly will significantly contribute to enhance the understanding of the adaptation mechanisms of the white-lipped deer to the extreme environments.
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spelling doaj-art-ab0384a3243e44a798d50e8ee4d1711b2025-08-20T03:52:24ZengNature PortfolioScientific Data2052-44632025-05-011211810.1038/s41597-025-04796-1A high-quality Chromosome-level reference genome assembly of white-lipped deer (Przewalskium albirostris)Yuangang Yang0Bin Li1Wei Luo2Bo Xu3Peng Luo4Tongzuo Zhang5Zhangqiang You6Ecological Security and Protection Key Laboratory of Sichuan Province, Mianyang Normal UniversityKey Laboratory of Adaptation and Evolution of Plateau Biota, Northwest Institute of Plateau Biology, Chinese Academy of SciencesEcological Security and Protection Key Laboratory of Sichuan Province, Mianyang Normal UniversityKey Laboratory of Adaptation and Evolution of Plateau Biota, Northwest Institute of Plateau Biology, Chinese Academy of SciencesEcological Security and Protection Key Laboratory of Sichuan Province, Mianyang Normal UniversityKey Laboratory of Adaptation and Evolution of Plateau Biota, Northwest Institute of Plateau Biology, Chinese Academy of SciencesEcological Security and Protection Key Laboratory of Sichuan Province, Mianyang Normal UniversityAbstract White-lipped deer (Przewalskium albirostris) is the sole species in the genus Przewalskium of the Cervidae family. And it is exclusively found in the Qinghai-Tibet Plateau, where it has evolved as a specialized deer on account of the extreme climates and geographical conditions. However, limited research on the genome of this species exists. Here, PacBio and Hi-C sequencing data were constructed to a high-quality Chromosome-level reference genome for the white-lipped deer. The assembly, totaling 2.99 GB, is composed of 34 chromosomes (32 autosomes and X, Y chromosomes), with a scaffold N50 length of 76.18 Mb. Furthermore, it achieved scores of 98.4% and 63.8 in Universal Single-Copy Ortholog (BUSCO) and quality value (QV), respectively. Subsequently, employing the egapx software for genome structural annotation, we identified a total of 21909 protein coding genes, annotating 21859 of them. The high-quality and completeness of our genome sequence and annotation was affirmed by these results. The assembly will significantly contribute to enhance the understanding of the adaptation mechanisms of the white-lipped deer to the extreme environments.https://doi.org/10.1038/s41597-025-04796-1
spellingShingle Yuangang Yang
Bin Li
Wei Luo
Bo Xu
Peng Luo
Tongzuo Zhang
Zhangqiang You
A high-quality Chromosome-level reference genome assembly of white-lipped deer (Przewalskium albirostris)
Scientific Data
title A high-quality Chromosome-level reference genome assembly of white-lipped deer (Przewalskium albirostris)
title_full A high-quality Chromosome-level reference genome assembly of white-lipped deer (Przewalskium albirostris)
title_fullStr A high-quality Chromosome-level reference genome assembly of white-lipped deer (Przewalskium albirostris)
title_full_unstemmed A high-quality Chromosome-level reference genome assembly of white-lipped deer (Przewalskium albirostris)
title_short A high-quality Chromosome-level reference genome assembly of white-lipped deer (Przewalskium albirostris)
title_sort high quality chromosome level reference genome assembly of white lipped deer przewalskium albirostris
url https://doi.org/10.1038/s41597-025-04796-1
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