Case Series: Organophosphate Contamination of Camel’s Mammary Glands Affects Human Health

In this case series, we present 2 cases of previously healthy farmers, who presented with symptoms of a cholinergic crisis that developed several hours after ingestion of camel milk. The initial case was treated with supportive medical care without using antidote as no history of direct exposure to...

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Main Authors: Maryam Saif Al Ali, Jasem Al Shamsi, Saweera Sabbar
Format: Article
Language:English
Published: Knowledge E 2020-09-01
Series:Dubai Medical Journal
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Online Access:https://www.karger.com/Article/FullText/510263
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author Maryam Saif Al Ali
Jasem Al Shamsi
Saweera Sabbar
author_facet Maryam Saif Al Ali
Jasem Al Shamsi
Saweera Sabbar
author_sort Maryam Saif Al Ali
collection DOAJ
description In this case series, we present 2 cases of previously healthy farmers, who presented with symptoms of a cholinergic crisis that developed several hours after ingestion of camel milk. The initial case was treated with supportive medical care without using antidote as no history of direct exposure to pesticides was available.The second case presented with symptoms of cholinergic crisis that developed several hours after the ingestion of camel milk. Clinical features included slurred speech, headache, vomiting, diarrhea, frequent ­micturition, muscle fasciculation, chest discomfort, and atrial fibrillation. The patient developed bradycardia that responded to intravenous atropine. Routine investigations were unremarkable, but acetylcholinesterase and pseudocholinesterase levels were both low. The patient was managed with intravenous fluids, analgesia, atropine, and pralidoxime, which were administered when he developed respiratory symptoms secondary to excessive secretions. The following day, the patient was asymptomatic and discharged. On the medical history, the patient denied any other ingestion including food and drink or potential organophosphate exposure on the day of symptom onset. Application of organophosphate pesticides to the mammary glands of camels has been used for many decades against Sarcoptes scabei cameli, a mite that causes a dermal infestation in camels similar to human scabies infections.
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spelling doaj-art-aafdedfc4dab4f33b158fa9de43a8b0e2025-08-20T02:42:52ZengKnowledge EDubai Medical Journal2571-726X2020-09-011310.1159/000510263510263Case Series: Organophosphate Contamination of Camel’s Mammary Glands Affects Human HealthMaryam Saif Al AliJasem Al ShamsiSaweera SabbarIn this case series, we present 2 cases of previously healthy farmers, who presented with symptoms of a cholinergic crisis that developed several hours after ingestion of camel milk. The initial case was treated with supportive medical care without using antidote as no history of direct exposure to pesticides was available.The second case presented with symptoms of cholinergic crisis that developed several hours after the ingestion of camel milk. Clinical features included slurred speech, headache, vomiting, diarrhea, frequent ­micturition, muscle fasciculation, chest discomfort, and atrial fibrillation. The patient developed bradycardia that responded to intravenous atropine. Routine investigations were unremarkable, but acetylcholinesterase and pseudocholinesterase levels were both low. The patient was managed with intravenous fluids, analgesia, atropine, and pralidoxime, which were administered when he developed respiratory symptoms secondary to excessive secretions. The following day, the patient was asymptomatic and discharged. On the medical history, the patient denied any other ingestion including food and drink or potential organophosphate exposure on the day of symptom onset. Application of organophosphate pesticides to the mammary glands of camels has been used for many decades against Sarcoptes scabei cameli, a mite that causes a dermal infestation in camels similar to human scabies infections.https://www.karger.com/Article/FullText/510263organophosphatepesticidescholinergic toxicitycamel milk
spellingShingle Maryam Saif Al Ali
Jasem Al Shamsi
Saweera Sabbar
Case Series: Organophosphate Contamination of Camel’s Mammary Glands Affects Human Health
Dubai Medical Journal
organophosphate
pesticides
cholinergic toxicity
camel milk
title Case Series: Organophosphate Contamination of Camel’s Mammary Glands Affects Human Health
title_full Case Series: Organophosphate Contamination of Camel’s Mammary Glands Affects Human Health
title_fullStr Case Series: Organophosphate Contamination of Camel’s Mammary Glands Affects Human Health
title_full_unstemmed Case Series: Organophosphate Contamination of Camel’s Mammary Glands Affects Human Health
title_short Case Series: Organophosphate Contamination of Camel’s Mammary Glands Affects Human Health
title_sort case series organophosphate contamination of camel s mammary glands affects human health
topic organophosphate
pesticides
cholinergic toxicity
camel milk
url https://www.karger.com/Article/FullText/510263
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AT jasemalshamsi caseseriesorganophosphatecontaminationofcamelsmammaryglandsaffectshumanhealth
AT saweerasabbar caseseriesorganophosphatecontaminationofcamelsmammaryglandsaffectshumanhealth