Morpho-phenotypic characterization of melanoma brain metastases immune microenvironment: A multicentre retrospective study

Morpho-phenotypic characterization of melanoma brain metastases immune microenvironment: A multicentre retrospective study

Introduction: The recent rise of immunotherapy for melanoma brain metastases (MBM) has enhanced the interest in characterizing the composition of local immune microenvironment. Despite the central nervous system (CNS) is well known for harbouring a peculiar immunological milieu, its role in MBM is o...

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Main Authors: Filippo Nozzoli, Marco Gessi, Filippo Ugolini, Sara Simi, Luca Tinunin, Luigi Francesco Iannone, Alice Esposito, Giovanni Muscas, Alessandro Della Puppa, Isabella Ciardetti, Nicola Pimpinelli, Vincenzo De Giorgi, Isacco Desideri, Lorenzo Livi, Laura Doni, Giovanni Schinzari, Ernesto Rossi, Mario Mandalà, Daniela Massi
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:EJC Skin Cancer
Subjects:
Melanoma
brain metastasis
tumour associated astrogliosis
tumour infiltrating lymphocytes (TILs)
tumour associated macrophages (TAMs)
tumor microenvironment (TME)
Online Access:http://www.sciencedirect.com/science/article/pii/S2772611824002519
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