Diagnostic Value and Safety of Emergency Single-Balloon Enteroscopy for Obscure Gastrointestinal Bleeding
Background. This study assesses the diagnostic performance of emergency single-balloon enteroscopy (SBE) for obscure gastrointestinal bleeding (OGIB) under general anesthesia versus conscious sedation. Study. The data of 102 OGIB in-patients from June 2015 to June 2018 were retrospectively analyzed....
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Wiley
2019-01-01
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| Series: | Gastroenterology Research and Practice |
| Online Access: | http://dx.doi.org/10.1155/2019/9026278 |
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| author | Yipin Liu Weiwei Jiang Guoxun Chen Yanqing Li |
| author_facet | Yipin Liu Weiwei Jiang Guoxun Chen Yanqing Li |
| author_sort | Yipin Liu |
| collection | DOAJ |
| description | Background. This study assesses the diagnostic performance of emergency single-balloon enteroscopy (SBE) for obscure gastrointestinal bleeding (OGIB) under general anesthesia versus conscious sedation. Study. The data of 102 OGIB in-patients from June 2015 to June 2018 were retrospectively analyzed. The diagnosis and detection rates and adverse events were calculated overall and in relation to age, gender, type of operation and anesthesia, bleeding type, different times of examination, and SBE route. All statistical analyses were performed using SPSS 24.0, and the diagnosis and detection rates were compared using the Chi-square test. Results. Among the 102 patients, 66 patients had positive findings, while 11 patients had suspected positive findings, and the diagnosis and detection rates were 64.7% and 75.5%, respectively. Ulcers (19.6%) and tumors (16.7%) were the most common causes of OGIB. There were no statistical differences in diagnosis and detection rates between the ages of ≥60 and <60 and between different genders. Patients with emergency SBE had higher diagnosis and detection rates (68.6% vs. 35.3%, P=0.023; 80.0% vs. 47.1%, P=0.016, respectively), when compared with nonemergency SBE patients. The diagnosis rate at 24 hours was higher than that at 2-7 days and one week (88.0% vs. 61.5%, P=0.030; 88.0% vs. 53.8%, P=0.007). For overt bleeding, the difference in diagnosis rates at 24 hours, 2-7 days, and one week was statistically significant (100.0% vs. 57.1%, P=0.006; 100.0% vs. 57.1%, P=0.006). For occult bleeding, the pairwise comparison revealed no statistical difference. Patients with general anesthesia had a higher detection rate, when compared to patients with conscious sedation (87.9% vs. 63.9%, P=0.004). In addition, adverse events under general anesthesia were lower, when compared to adverse events under conscious sedation (28.8% vs. 69.4%, P=0.020). There was no significant difference in adverse events at the different time points (P>0.05). Conclusion. Emergency SBE under general anesthesia achieves higher diagnosis and detection rates, and fewer adverse events under conscious sedation, when compared to nonemergency SBE, regardless of the route. For patients with overt bleeding, it is easier to find lesions by emergency SBE within 24 hours. |
| format | Article |
| id | doaj-art-aaedceefc18340108cee346f724f10e1 |
| institution | OA Journals |
| issn | 1687-6121 1687-630X |
| language | English |
| publishDate | 2019-01-01 |
| publisher | Wiley |
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| series | Gastroenterology Research and Practice |
| spelling | doaj-art-aaedceefc18340108cee346f724f10e12025-08-20T02:20:12ZengWileyGastroenterology Research and Practice1687-61211687-630X2019-01-01201910.1155/2019/90262789026278Diagnostic Value and Safety of Emergency Single-Balloon Enteroscopy for Obscure Gastrointestinal BleedingYipin Liu0Weiwei Jiang1Guoxun Chen2Yanqing Li3Department of Gastroenterology, Qilu Hospital, Shandong University, Jinan, Shandong Province 250012, ChinaDepartment of Gastroenterology, Yantai Affiliated Hospital of Binzhou Medical University, Yantai, Shandong Province 264000, ChinaDepartment of Nutrition, University of Tennessee, Knoxville, Tennessee 37909, USADepartment of Gastroenterology, Qilu Hospital, Shandong University, Jinan, Shandong Province 250012, ChinaBackground. This study assesses the diagnostic performance of emergency single-balloon enteroscopy (SBE) for obscure gastrointestinal bleeding (OGIB) under general anesthesia versus conscious sedation. Study. The data of 102 OGIB in-patients from June 2015 to June 2018 were retrospectively analyzed. The diagnosis and detection rates and adverse events were calculated overall and in relation to age, gender, type of operation and anesthesia, bleeding type, different times of examination, and SBE route. All statistical analyses were performed using SPSS 24.0, and the diagnosis and detection rates were compared using the Chi-square test. Results. Among the 102 patients, 66 patients had positive findings, while 11 patients had suspected positive findings, and the diagnosis and detection rates were 64.7% and 75.5%, respectively. Ulcers (19.6%) and tumors (16.7%) were the most common causes of OGIB. There were no statistical differences in diagnosis and detection rates between the ages of ≥60 and <60 and between different genders. Patients with emergency SBE had higher diagnosis and detection rates (68.6% vs. 35.3%, P=0.023; 80.0% vs. 47.1%, P=0.016, respectively), when compared with nonemergency SBE patients. The diagnosis rate at 24 hours was higher than that at 2-7 days and one week (88.0% vs. 61.5%, P=0.030; 88.0% vs. 53.8%, P=0.007). For overt bleeding, the difference in diagnosis rates at 24 hours, 2-7 days, and one week was statistically significant (100.0% vs. 57.1%, P=0.006; 100.0% vs. 57.1%, P=0.006). For occult bleeding, the pairwise comparison revealed no statistical difference. Patients with general anesthesia had a higher detection rate, when compared to patients with conscious sedation (87.9% vs. 63.9%, P=0.004). In addition, adverse events under general anesthesia were lower, when compared to adverse events under conscious sedation (28.8% vs. 69.4%, P=0.020). There was no significant difference in adverse events at the different time points (P>0.05). Conclusion. Emergency SBE under general anesthesia achieves higher diagnosis and detection rates, and fewer adverse events under conscious sedation, when compared to nonemergency SBE, regardless of the route. For patients with overt bleeding, it is easier to find lesions by emergency SBE within 24 hours.http://dx.doi.org/10.1155/2019/9026278 |
| spellingShingle | Yipin Liu Weiwei Jiang Guoxun Chen Yanqing Li Diagnostic Value and Safety of Emergency Single-Balloon Enteroscopy for Obscure Gastrointestinal Bleeding Gastroenterology Research and Practice |
| title | Diagnostic Value and Safety of Emergency Single-Balloon Enteroscopy for Obscure Gastrointestinal Bleeding |
| title_full | Diagnostic Value and Safety of Emergency Single-Balloon Enteroscopy for Obscure Gastrointestinal Bleeding |
| title_fullStr | Diagnostic Value and Safety of Emergency Single-Balloon Enteroscopy for Obscure Gastrointestinal Bleeding |
| title_full_unstemmed | Diagnostic Value and Safety of Emergency Single-Balloon Enteroscopy for Obscure Gastrointestinal Bleeding |
| title_short | Diagnostic Value and Safety of Emergency Single-Balloon Enteroscopy for Obscure Gastrointestinal Bleeding |
| title_sort | diagnostic value and safety of emergency single balloon enteroscopy for obscure gastrointestinal bleeding |
| url | http://dx.doi.org/10.1155/2019/9026278 |
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