Trends of Candida species causing bloodstream infections in South-Eastern Asia: A systematic review and meta-analysis

A reliable estimation of Candida bloodstream infection prevalence is increasingly important to track changes in Candida species distribution and define burden of ongoing candidemia. A systematic review and meta-analysis were conducted to estimate candidemia prevalence and identify patterns of Candid...

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Main Authors: Dina Yamin, Abubakar Muhammad Wakil, Mohammed Dauda Goni, Ahmad Adebayo Irekeola, Khalid Hajissa
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2025-01-01
Series:Asian Pacific Journal of Tropical Medicine
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Online Access:https://journals.lww.com/10.4103/apjtm.apjtm_559_24
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author Dina Yamin
Abubakar Muhammad Wakil
Mohammed Dauda Goni
Ahmad Adebayo Irekeola
Khalid Hajissa
author_facet Dina Yamin
Abubakar Muhammad Wakil
Mohammed Dauda Goni
Ahmad Adebayo Irekeola
Khalid Hajissa
author_sort Dina Yamin
collection DOAJ
description A reliable estimation of Candida bloodstream infection prevalence is increasingly important to track changes in Candida species distribution and define burden of ongoing candidemia. A systematic review and meta-analysis were conducted to estimate candidemia prevalence and identify patterns of Candida species in South-eastern Asia. Systematic electronic-databases literature search was performed on published studies recorded candidemia prevalence in South-Eastern Asia. Using meta-analysis of proportions, the overall pooled prevalences of candidemia by Candida (C.) albicans, C. tropicalis, C. parapsilosis and C. glabrata were calculated as 28.4% (95% CI 24.9-31.8), 29.2% (95% CI 24.7-33.7), 19.1% (95% CI 14.8-23.4) and 14.0% (95% CI 10.4-17.5), respectively. Based on publication year and country, subgroup analyses were conducted on Candida species to determine heterogeneity source. The findings may not precisely reflect true candidemia prevalence in different countries. Therefore, it highlights continuous need to conduct prevalence studies, assess and monitor growing burden, control effect of potential risk factors and implement regional surveillance programs to prevent further rise.
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issn 2352-4146
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publisher Wolters Kluwer Medknow Publications
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series Asian Pacific Journal of Tropical Medicine
spelling doaj-art-aae6c9c8ede04ec09dfefdabe752cb3f2025-08-20T02:56:30ZengWolters Kluwer Medknow PublicationsAsian Pacific Journal of Tropical Medicine2352-41462025-01-01182516610.4103/apjtm.apjtm_559_24Trends of Candida species causing bloodstream infections in South-Eastern Asia: A systematic review and meta-analysisDina YaminAbubakar Muhammad WakilMohammed Dauda GoniAhmad Adebayo IrekeolaKhalid HajissaA reliable estimation of Candida bloodstream infection prevalence is increasingly important to track changes in Candida species distribution and define burden of ongoing candidemia. A systematic review and meta-analysis were conducted to estimate candidemia prevalence and identify patterns of Candida species in South-eastern Asia. Systematic electronic-databases literature search was performed on published studies recorded candidemia prevalence in South-Eastern Asia. Using meta-analysis of proportions, the overall pooled prevalences of candidemia by Candida (C.) albicans, C. tropicalis, C. parapsilosis and C. glabrata were calculated as 28.4% (95% CI 24.9-31.8), 29.2% (95% CI 24.7-33.7), 19.1% (95% CI 14.8-23.4) and 14.0% (95% CI 10.4-17.5), respectively. Based on publication year and country, subgroup analyses were conducted on Candida species to determine heterogeneity source. The findings may not precisely reflect true candidemia prevalence in different countries. Therefore, it highlights continuous need to conduct prevalence studies, assess and monitor growing burden, control effect of potential risk factors and implement regional surveillance programs to prevent further rise.https://journals.lww.com/10.4103/apjtm.apjtm_559_24candida speciescandidemiabloodstream infectionsprevalencesouth-eastern asiasystematic review and meta-analysis
spellingShingle Dina Yamin
Abubakar Muhammad Wakil
Mohammed Dauda Goni
Ahmad Adebayo Irekeola
Khalid Hajissa
Trends of Candida species causing bloodstream infections in South-Eastern Asia: A systematic review and meta-analysis
Asian Pacific Journal of Tropical Medicine
candida species
candidemia
bloodstream infections
prevalence
south-eastern asia
systematic review and meta-analysis
title Trends of Candida species causing bloodstream infections in South-Eastern Asia: A systematic review and meta-analysis
title_full Trends of Candida species causing bloodstream infections in South-Eastern Asia: A systematic review and meta-analysis
title_fullStr Trends of Candida species causing bloodstream infections in South-Eastern Asia: A systematic review and meta-analysis
title_full_unstemmed Trends of Candida species causing bloodstream infections in South-Eastern Asia: A systematic review and meta-analysis
title_short Trends of Candida species causing bloodstream infections in South-Eastern Asia: A systematic review and meta-analysis
title_sort trends of candida species causing bloodstream infections in south eastern asia a systematic review and meta analysis
topic candida species
candidemia
bloodstream infections
prevalence
south-eastern asia
systematic review and meta-analysis
url https://journals.lww.com/10.4103/apjtm.apjtm_559_24
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AT mohammeddaudagoni trendsofcandidaspeciescausingbloodstreaminfectionsinsoutheasternasiaasystematicreviewandmetaanalysis
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