Unusual Extramedullary Plasmacytoma: A Rare but Possible Cause of Lymphadenopathy in Chronic Lymphocytic Leukemia
Cervical bilateral lymphadenopathy is a frequent event during chronic lymphocytic leukemia (CLL) natural history. However, lymph node biopsy is generally not required as long as transformation into an aggressive lymphoma (Richter syndrome) is not suspected. We present here a rare case of CLL patient...
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Wiley
2015-01-01
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Series: | Case Reports in Medicine |
Online Access: | http://dx.doi.org/10.1155/2015/657049 |
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author | S. P. Chantepie Q. Cabrera J. B. Mear V. Salaun E. Lechapt-Zalcman M. Macro |
author_facet | S. P. Chantepie Q. Cabrera J. B. Mear V. Salaun E. Lechapt-Zalcman M. Macro |
author_sort | S. P. Chantepie |
collection | DOAJ |
description | Cervical bilateral lymphadenopathy is a frequent event during chronic lymphocytic leukemia (CLL) natural history. However, lymph node biopsy is generally not required as long as transformation into an aggressive lymphoma (Richter syndrome) is not suspected. We present here a rare case of CLL patient who developed progressive bilateral cervical lymph node and bilateral tonsillar hypertrophy. CLL front-line therapy was ineffective leading to adenectomy and diagnosis of concomitant extramedullary plasmacytoma. Radiotherapy did not result in the disappearance of lymphadenopathy. Adenectomy should be performed in CLL cases to avoid misdiagnosis. |
format | Article |
id | doaj-art-aac5dfcd98164df08bb9343a8274c643 |
institution | Kabale University |
issn | 1687-9627 1687-9635 |
language | English |
publishDate | 2015-01-01 |
publisher | Wiley |
record_format | Article |
series | Case Reports in Medicine |
spelling | doaj-art-aac5dfcd98164df08bb9343a8274c6432025-02-03T05:45:36ZengWileyCase Reports in Medicine1687-96271687-96352015-01-01201510.1155/2015/657049657049Unusual Extramedullary Plasmacytoma: A Rare but Possible Cause of Lymphadenopathy in Chronic Lymphocytic LeukemiaS. P. Chantepie0Q. Cabrera1J. B. Mear2V. Salaun3E. Lechapt-Zalcman4M. Macro5Department of Hematology, Caen University Hospital, 14000 Caen, FranceDepartment of Hematology, Caen University Hospital, 14000 Caen, FranceDepartment of Hematology, Caen University Hospital, 14000 Caen, FranceHematology Laboratory, Caen University Hospital, 14000 Caen, FranceDepartment of Pathology, Caen University Hospital, 14000 Caen, FranceDepartment of Hematology, Caen University Hospital, 14000 Caen, FranceCervical bilateral lymphadenopathy is a frequent event during chronic lymphocytic leukemia (CLL) natural history. However, lymph node biopsy is generally not required as long as transformation into an aggressive lymphoma (Richter syndrome) is not suspected. We present here a rare case of CLL patient who developed progressive bilateral cervical lymph node and bilateral tonsillar hypertrophy. CLL front-line therapy was ineffective leading to adenectomy and diagnosis of concomitant extramedullary plasmacytoma. Radiotherapy did not result in the disappearance of lymphadenopathy. Adenectomy should be performed in CLL cases to avoid misdiagnosis.http://dx.doi.org/10.1155/2015/657049 |
spellingShingle | S. P. Chantepie Q. Cabrera J. B. Mear V. Salaun E. Lechapt-Zalcman M. Macro Unusual Extramedullary Plasmacytoma: A Rare but Possible Cause of Lymphadenopathy in Chronic Lymphocytic Leukemia Case Reports in Medicine |
title | Unusual Extramedullary Plasmacytoma: A Rare but Possible Cause of Lymphadenopathy in Chronic Lymphocytic Leukemia |
title_full | Unusual Extramedullary Plasmacytoma: A Rare but Possible Cause of Lymphadenopathy in Chronic Lymphocytic Leukemia |
title_fullStr | Unusual Extramedullary Plasmacytoma: A Rare but Possible Cause of Lymphadenopathy in Chronic Lymphocytic Leukemia |
title_full_unstemmed | Unusual Extramedullary Plasmacytoma: A Rare but Possible Cause of Lymphadenopathy in Chronic Lymphocytic Leukemia |
title_short | Unusual Extramedullary Plasmacytoma: A Rare but Possible Cause of Lymphadenopathy in Chronic Lymphocytic Leukemia |
title_sort | unusual extramedullary plasmacytoma a rare but possible cause of lymphadenopathy in chronic lymphocytic leukemia |
url | http://dx.doi.org/10.1155/2015/657049 |
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