Unusual Extramedullary Plasmacytoma: A Rare but Possible Cause of Lymphadenopathy in Chronic Lymphocytic Leukemia

Cervical bilateral lymphadenopathy is a frequent event during chronic lymphocytic leukemia (CLL) natural history. However, lymph node biopsy is generally not required as long as transformation into an aggressive lymphoma (Richter syndrome) is not suspected. We present here a rare case of CLL patient...

Full description

Saved in:
Bibliographic Details
Main Authors: S. P. Chantepie, Q. Cabrera, J. B. Mear, V. Salaun, E. Lechapt-Zalcman, M. Macro
Format: Article
Language:English
Published: Wiley 2015-01-01
Series:Case Reports in Medicine
Online Access:http://dx.doi.org/10.1155/2015/657049
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1832556351671238656
author S. P. Chantepie
Q. Cabrera
J. B. Mear
V. Salaun
E. Lechapt-Zalcman
M. Macro
author_facet S. P. Chantepie
Q. Cabrera
J. B. Mear
V. Salaun
E. Lechapt-Zalcman
M. Macro
author_sort S. P. Chantepie
collection DOAJ
description Cervical bilateral lymphadenopathy is a frequent event during chronic lymphocytic leukemia (CLL) natural history. However, lymph node biopsy is generally not required as long as transformation into an aggressive lymphoma (Richter syndrome) is not suspected. We present here a rare case of CLL patient who developed progressive bilateral cervical lymph node and bilateral tonsillar hypertrophy. CLL front-line therapy was ineffective leading to adenectomy and diagnosis of concomitant extramedullary plasmacytoma. Radiotherapy did not result in the disappearance of lymphadenopathy. Adenectomy should be performed in CLL cases to avoid misdiagnosis.
format Article
id doaj-art-aac5dfcd98164df08bb9343a8274c643
institution Kabale University
issn 1687-9627
1687-9635
language English
publishDate 2015-01-01
publisher Wiley
record_format Article
series Case Reports in Medicine
spelling doaj-art-aac5dfcd98164df08bb9343a8274c6432025-02-03T05:45:36ZengWileyCase Reports in Medicine1687-96271687-96352015-01-01201510.1155/2015/657049657049Unusual Extramedullary Plasmacytoma: A Rare but Possible Cause of Lymphadenopathy in Chronic Lymphocytic LeukemiaS. P. Chantepie0Q. Cabrera1J. B. Mear2V. Salaun3E. Lechapt-Zalcman4M. Macro5Department of Hematology, Caen University Hospital, 14000 Caen, FranceDepartment of Hematology, Caen University Hospital, 14000 Caen, FranceDepartment of Hematology, Caen University Hospital, 14000 Caen, FranceHematology Laboratory, Caen University Hospital, 14000 Caen, FranceDepartment of Pathology, Caen University Hospital, 14000 Caen, FranceDepartment of Hematology, Caen University Hospital, 14000 Caen, FranceCervical bilateral lymphadenopathy is a frequent event during chronic lymphocytic leukemia (CLL) natural history. However, lymph node biopsy is generally not required as long as transformation into an aggressive lymphoma (Richter syndrome) is not suspected. We present here a rare case of CLL patient who developed progressive bilateral cervical lymph node and bilateral tonsillar hypertrophy. CLL front-line therapy was ineffective leading to adenectomy and diagnosis of concomitant extramedullary plasmacytoma. Radiotherapy did not result in the disappearance of lymphadenopathy. Adenectomy should be performed in CLL cases to avoid misdiagnosis.http://dx.doi.org/10.1155/2015/657049
spellingShingle S. P. Chantepie
Q. Cabrera
J. B. Mear
V. Salaun
E. Lechapt-Zalcman
M. Macro
Unusual Extramedullary Plasmacytoma: A Rare but Possible Cause of Lymphadenopathy in Chronic Lymphocytic Leukemia
Case Reports in Medicine
title Unusual Extramedullary Plasmacytoma: A Rare but Possible Cause of Lymphadenopathy in Chronic Lymphocytic Leukemia
title_full Unusual Extramedullary Plasmacytoma: A Rare but Possible Cause of Lymphadenopathy in Chronic Lymphocytic Leukemia
title_fullStr Unusual Extramedullary Plasmacytoma: A Rare but Possible Cause of Lymphadenopathy in Chronic Lymphocytic Leukemia
title_full_unstemmed Unusual Extramedullary Plasmacytoma: A Rare but Possible Cause of Lymphadenopathy in Chronic Lymphocytic Leukemia
title_short Unusual Extramedullary Plasmacytoma: A Rare but Possible Cause of Lymphadenopathy in Chronic Lymphocytic Leukemia
title_sort unusual extramedullary plasmacytoma a rare but possible cause of lymphadenopathy in chronic lymphocytic leukemia
url http://dx.doi.org/10.1155/2015/657049
work_keys_str_mv AT spchantepie unusualextramedullaryplasmacytomaararebutpossiblecauseoflymphadenopathyinchroniclymphocyticleukemia
AT qcabrera unusualextramedullaryplasmacytomaararebutpossiblecauseoflymphadenopathyinchroniclymphocyticleukemia
AT jbmear unusualextramedullaryplasmacytomaararebutpossiblecauseoflymphadenopathyinchroniclymphocyticleukemia
AT vsalaun unusualextramedullaryplasmacytomaararebutpossiblecauseoflymphadenopathyinchroniclymphocyticleukemia
AT elechaptzalcman unusualextramedullaryplasmacytomaararebutpossiblecauseoflymphadenopathyinchroniclymphocyticleukemia
AT mmacro unusualextramedullaryplasmacytomaararebutpossiblecauseoflymphadenopathyinchroniclymphocyticleukemia