THE MODERN METHODS OF ANALYSIS OF OXIDIZED AND REDUCED FORMS OF COENZYME Q₁₀ IN BIOMATERIAL (REVIEW)
In the human body, coenzyme Q10 is in the oxidized and reduced forms and can be found in every organ. The review describes modern HPLC methods of coenzyme Q10 analysis using electrochemical, spectrophotometric and mass spectrometric detectors. In the article we present information on sampling, prepa...
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| Format: | Article |
| Language: | Russian |
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LLC Center of Pharmaceutical Analytics (LLC «CPHA»)
2019-01-01
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| Series: | Разработка и регистрация лекарственных средств |
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| Online Access: | https://www.pharmjournal.ru/jour/article/view/550 |
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| _version_ | 1849243916388270080 |
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| author | V. I. Zozina O. A. Goroshko L. M. Krasnykh V. G. Kukes |
| author_facet | V. I. Zozina O. A. Goroshko L. M. Krasnykh V. G. Kukes |
| author_sort | V. I. Zozina |
| collection | DOAJ |
| description | In the human body, coenzyme Q10 is in the oxidized and reduced forms and can be found in every organ. The review describes modern HPLC methods of coenzyme Q10 analysis using electrochemical, spectrophotometric and mass spectrometric detectors. In the article we present information on sampling, preparation of biomaterial for analysis and preservation of coenzyme Q10 stability in biomaterial. It is carried out a comparative analysis of the determination methodologies for the oxidized and reduced forms of coenzyme Q10 by its sensitivity and selectivity. |
| format | Article |
| id | doaj-art-aabeadcb51b545108fd0e91deb3e7c98 |
| institution | Kabale University |
| issn | 2305-2066 2658-5049 |
| language | Russian |
| publishDate | 2019-01-01 |
| publisher | LLC Center of Pharmaceutical Analytics (LLC «CPHA») |
| record_format | Article |
| series | Разработка и регистрация лекарственных средств |
| spelling | doaj-art-aabeadcb51b545108fd0e91deb3e7c982025-08-20T03:59:20ZrusLLC Center of Pharmaceutical Analytics (LLC «CPHA»)Разработка и регистрация лекарственных средств2305-20662658-50492019-01-01018488550THE MODERN METHODS OF ANALYSIS OF OXIDIZED AND REDUCED FORMS OF COENZYME Q₁₀ IN BIOMATERIAL (REVIEW)V. I. Zozina0O. A. Goroshko1L. M. Krasnykh2V. G. Kukes3I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian FederationScientific Centre for Expert Evaluation of Medical Products of the Ministry of Health of the Russian FederationScientific Centre for Expert Evaluation of Medical Products of the Ministry of Health of the Russian FederationI.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation; Scientific Centre for Expert Evaluation of Medical Products of the Ministry of Health of the Russian FederationIn the human body, coenzyme Q10 is in the oxidized and reduced forms and can be found in every organ. The review describes modern HPLC methods of coenzyme Q10 analysis using electrochemical, spectrophotometric and mass spectrometric detectors. In the article we present information on sampling, preparation of biomaterial for analysis and preservation of coenzyme Q10 stability in biomaterial. It is carried out a comparative analysis of the determination methodologies for the oxidized and reduced forms of coenzyme Q10 by its sensitivity and selectivity.https://www.pharmjournal.ru/jour/article/view/550сoenzyme q₁₀ubiquinoneubiquinolhplc |
| spellingShingle | V. I. Zozina O. A. Goroshko L. M. Krasnykh V. G. Kukes THE MODERN METHODS OF ANALYSIS OF OXIDIZED AND REDUCED FORMS OF COENZYME Q₁₀ IN BIOMATERIAL (REVIEW) Разработка и регистрация лекарственных средств сoenzyme q₁₀ ubiquinone ubiquinol hplc |
| title | THE MODERN METHODS OF ANALYSIS OF OXIDIZED AND REDUCED FORMS OF COENZYME Q₁₀ IN BIOMATERIAL (REVIEW) |
| title_full | THE MODERN METHODS OF ANALYSIS OF OXIDIZED AND REDUCED FORMS OF COENZYME Q₁₀ IN BIOMATERIAL (REVIEW) |
| title_fullStr | THE MODERN METHODS OF ANALYSIS OF OXIDIZED AND REDUCED FORMS OF COENZYME Q₁₀ IN BIOMATERIAL (REVIEW) |
| title_full_unstemmed | THE MODERN METHODS OF ANALYSIS OF OXIDIZED AND REDUCED FORMS OF COENZYME Q₁₀ IN BIOMATERIAL (REVIEW) |
| title_short | THE MODERN METHODS OF ANALYSIS OF OXIDIZED AND REDUCED FORMS OF COENZYME Q₁₀ IN BIOMATERIAL (REVIEW) |
| title_sort | modern methods of analysis of oxidized and reduced forms of coenzyme q₁₀ in biomaterial review |
| topic | сoenzyme q₁₀ ubiquinone ubiquinol hplc |
| url | https://www.pharmjournal.ru/jour/article/view/550 |
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