Severe Hypoalbuminemia Following Mini Gastric Bypass Surgery: A Case Report

Background: Severe obesity is a major public health issue affecting health and life expectancy. Bariatric surgery is one of the most effective treatments for managing severe obesity, facilitating significant weight loss, and improving or resolving comorbid conditions like type 2 diabetes (T2DM), hyp...

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Main Authors: Melika Shojaei, Fatemeh Nekouei, Maryam Nekooei
Format: Article
Language:English
Published: Bushehr University of Medical Sciences 2025-02-01
Series:Iranian South Medical Journal
Subjects:
Online Access:http://ismj.bpums.ac.ir/article-1-2095-en.pdf
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author Melika Shojaei
Fatemeh Nekouei
Maryam Nekooei
author_facet Melika Shojaei
Fatemeh Nekouei
Maryam Nekooei
author_sort Melika Shojaei
collection DOAJ
description Background: Severe obesity is a major public health issue affecting health and life expectancy. Bariatric surgery is one of the most effective treatments for managing severe obesity, facilitating significant weight loss, and improving or resolving comorbid conditions like type 2 diabetes (T2DM), hypertension (HTN), and sleep apnea. However, despite successful weight loss, it may lead to nutritional complications, including hypoalbuminemia, anemia, hypocalcemia, and pancytopenia. Case Presentation: A 32-year-old woman with a BMI of 42.5 kg/m² underwent mini gastric bypass surgery with a 150 cm biliopancreatic limb (BPL). Post-surgery, her weight decreased to 66 kg, resulting in a 120% reduction in BMI. Approximately 2.5 years later, she developed weakness, lethargy, and difficulty performing daily activities. Clinical evaluations revealed significant hypoalbuminemia. The patient received only two injections of albumin, and has been treated with a high-protein diet and daily protein supplements since then, which corrected the hypoalbuminemia. Conclusion: BPL length, type of surgery, and patient age and gender should all be considered for selecting patients for bariatric surgery in order to minimize complications like hypoalbuminemia. If complications occur, the initial management should focus on nutritional interventions. Surgical revision, such as reopening the anastomosis, should be considered only when conservative treatments fail. This case underscores the importance of careful surgical planning, thorough evaluation, and adherence to nutritional protocols to prevent complications. Future research should explore factors affecting nutritional and metabolic outcomes and develop preventive strategies.
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spelling doaj-art-aabde4f4631d4a46a5cbc0d9525191d32025-08-20T03:01:47ZengBushehr University of Medical SciencesIranian South Medical Journal1735-43741735-69542025-02-01274319326Severe Hypoalbuminemia Following Mini Gastric Bypass Surgery: A Case ReportMelika Shojaei0Fatemeh Nekouei1Maryam Nekooei2 Department of Internal Medicine, School of Medicine, Bushehr University of Medical Sciences, Bu-shehr, Iran Student Research Committee, Bushehr University of Medical Sciences, Bushehr, Iran Department of Biochemistry, School of Medicine, Bushehr University of Medical Sciences, Bushehr, Iran Background: Severe obesity is a major public health issue affecting health and life expectancy. Bariatric surgery is one of the most effective treatments for managing severe obesity, facilitating significant weight loss, and improving or resolving comorbid conditions like type 2 diabetes (T2DM), hypertension (HTN), and sleep apnea. However, despite successful weight loss, it may lead to nutritional complications, including hypoalbuminemia, anemia, hypocalcemia, and pancytopenia. Case Presentation: A 32-year-old woman with a BMI of 42.5 kg/m² underwent mini gastric bypass surgery with a 150 cm biliopancreatic limb (BPL). Post-surgery, her weight decreased to 66 kg, resulting in a 120% reduction in BMI. Approximately 2.5 years later, she developed weakness, lethargy, and difficulty performing daily activities. Clinical evaluations revealed significant hypoalbuminemia. The patient received only two injections of albumin, and has been treated with a high-protein diet and daily protein supplements since then, which corrected the hypoalbuminemia. Conclusion: BPL length, type of surgery, and patient age and gender should all be considered for selecting patients for bariatric surgery in order to minimize complications like hypoalbuminemia. If complications occur, the initial management should focus on nutritional interventions. Surgical revision, such as reopening the anastomosis, should be considered only when conservative treatments fail. This case underscores the importance of careful surgical planning, thorough evaluation, and adherence to nutritional protocols to prevent complications. Future research should explore factors affecting nutritional and metabolic outcomes and develop preventive strategies.http://ismj.bpums.ac.ir/article-1-2095-en.pdfmini gastric bypasshypoalbuminemiasingle anastomosis gastric bypassroux-en-y gastric bypass
spellingShingle Melika Shojaei
Fatemeh Nekouei
Maryam Nekooei
Severe Hypoalbuminemia Following Mini Gastric Bypass Surgery: A Case Report
Iranian South Medical Journal
mini gastric bypass
hypoalbuminemia
single anastomosis gastric bypass
roux-en-y gastric bypass
title Severe Hypoalbuminemia Following Mini Gastric Bypass Surgery: A Case Report
title_full Severe Hypoalbuminemia Following Mini Gastric Bypass Surgery: A Case Report
title_fullStr Severe Hypoalbuminemia Following Mini Gastric Bypass Surgery: A Case Report
title_full_unstemmed Severe Hypoalbuminemia Following Mini Gastric Bypass Surgery: A Case Report
title_short Severe Hypoalbuminemia Following Mini Gastric Bypass Surgery: A Case Report
title_sort severe hypoalbuminemia following mini gastric bypass surgery a case report
topic mini gastric bypass
hypoalbuminemia
single anastomosis gastric bypass
roux-en-y gastric bypass
url http://ismj.bpums.ac.ir/article-1-2095-en.pdf
work_keys_str_mv AT melikashojaei severehypoalbuminemiafollowingminigastricbypasssurgeryacasereport
AT fatemehnekouei severehypoalbuminemiafollowingminigastricbypasssurgeryacasereport
AT maryamnekooei severehypoalbuminemiafollowingminigastricbypasssurgeryacasereport